This perspective article gathers the latest developments in mathematical and computational oncology tools that exploit network approaches for modelling, analysis, simulation of cancer development therapy design. It instigates community to explore new paths synergies under umbrella Special Issue “Networks Cancer: From Symmetry Breaking Targeted Therapy”. The focus is demonstrate how networks can...

Railway interlocking system is a distributed, safety, monetary and environmentally critical system and its failure may cause the loss of human life, severe injuries, loss of money and environmental damages. The complexity of this system requires formal modeling and step by step refinement for its construction and development. The formal specification-based languages, such as V DM , Z-notation a...

This paper introduces a new framework for realtime decision making in video games. An Ensemble agent is a compound agent composed of multiple agents, each with its own tasks or goals to achieve. Usually when dealing with real-time decision making, reactive agents are used; that is agents that return a decision based on the current state. While reactive agents are very fast, most games require m...

What processes can explain how very large populations are able to converge on the use of a particular word or grammatical construction without global coordination? Answering this question helps to understand why new language constructs usually propagate along an S-shaped curve with a rather sudden transition towards global agreement. It also helps to analyze and design new technologies that sup...

What processes can explain how very large populations are able to converge on the use of a particular word or grammatical construction without global coordination? Answering this question helps to understand why new language constructs usually propagate along an S-shaped curve with a rather sudden transition towards global agreement. It also helps to analyze and design new technologies that sup...

In their seminal paper of 1981, Knuth and Plass described how to apply the method of discrete dynamic programming to the problem of breaking a paragraph into lines. This paper outlines how the same method can be applied to the problem of page make up, or in other words breaking paragraphs into pages. One of the key ideas is that there must be interaction between the line breaking and page break...

As the coupling in a heterogeneous excitable medium is reduced, three different types of behavior are encountered: plane waves propagate without breaking up, plane waves break up into spiral waves, and plane waves block. We illustrate these phenomena in monolayers of chick embryonic heart cells using calcium sensitive fluorescent dyes. Following the addition of heptanol, an agent that reduces t...

This paper presents a model of a satellite communication system using evolving multi-agent architecture. Situations such as satellite communications link analysis and resource allocation, require dynamical making and breaking of links between communication nodes, and would highly benefit from increased on-board adaptability and autonomy. An evolvable architecture based on intelligent agents tha...