background: in recent years, neoadjuvant chemoradiation and subsequent surgical resection with total mesorectal excision has been shown to increase local control with decreased toxicity. neoadjuvant chemoradiotherapy is the standard treatment for locally advanced rectal cancer. in this study we evaluated the efficacy a cox-2 inhibitor on pathologic response, sphincter preservation and acute tox...

BACKGROUND AND PURPOSE Diffusion tensor metrics are potential in vivo quantitative neuroimaging biomarkers for the characterization of brain tumor subtype. This meta-analysis analyzes the ability of mean diffusivity and fractional anisotropy to distinguish low-grade from high-grade gliomas in the identifiable tumor core and the region of peripheral edema. MATERIALS AND METHODS A meta-analysis...

The overexpression of COX enzymes has been demonstrated in human neoplasms at various sites, including the colon, gastrointestinal tract, lung, skin and recently in brain tumors. In this study, COX-2 receptor overexpression in primary childhood brain tumors was determined and the distribution pattern of COX-2 receptors was examined. A sensitive, 4-step, alkaline phosphatase conjugated antigen d...

INTRODUCTION The differentiation of metastatic and primary brain tumors with certainty is important since clinical management and treatment of these two types of tumors are radically different. The purpose of the present study was to evaluate the effect of peritumoral edema volume, tumor volume and mass effect of tumor on differential diagnosis of metastatic and primary brain tumors. Also we ha...

Cystic formation in human primary brain tumors is a relatively rare event whose incidence varies widely according to the histotype of tumor. Composition cystic fluid has mostly been characterized samples collected at time tumor resection and no indications evolution content are available. We proteome using bottom-up proteomic approach on sequential obtained from secretory meningioma (SM), schwa...

Primary brain tumors arise from various cell types of the brain, including glial cells, neurons, neuroglial precursor cells, pinealocytes, pericytes of the vessels, cells of the hypophysis, lymphocytes and the meninges [1, 2]. The incidence of primary brain tumors varies between subtypes, with the most common primary brain tumors in adults being gliomas and meningiomas. Gliomas can be histologi...

The paper introduces an efficient method for detection and grading of Astrocytoma, a type of brain tumor in MR Brain Images. Gray Level Co-occurrence Matrix (GLCM) is applied to Image to get information like entropy, energy, contrast, correlation and ratio of brain tumor to the MR Image etc. These are used for creation of knowledge base. After training of ANN with input and target matrix, the A...

background : the association of the mobile phone use and risk of brain tumor remains controversial among radiationepidemiologists. methods : we hypothesized if an association between brain tumor and mobile phone use exists, this association will be manifested as a cohort effect (as a proxy of association between mobile phone use and brain tumor) in the incidence rates of brain tumor during the ...

Pilocytic astrocytoma (PA) is a low grade benign tumor, commonly occurs in Cerebellum (42-60%), Optic & hypothalamic region (9-30%), Brain Stem (9%). They rarely spread. It within the ventricle. In this report, we described our experience with cranial pilocytic 14-year-old child, who initially treated near total decompression of tumor. Four and half years later, recurrence primary tumor obs...

Hypoxia is known to be an important prognostic marker in many human cancers. We report the use of two oxygen measurement techniques in human brain tumors and compare these data with semiquantitative histological end points. Oxygenation was measured using the Eppendorf needle electrode and/or EF5 binding in 28 brain tumors. These data were compared with necrosis, mitosis, and endothelial prolife...