When treating childhood acute lymphoblastic leukemia (ALL), secondary neoplasms are a significant long term problem. Radiation is generally accepted to be a major cause of the development of secondary neoplasms. Following treatment for ALL, a variety of secondary tumors, including brain tumors, hematologic malignancies, sarcomas, thyroid cancers, and skin cancers have been reported. However, ol...

Gliosarcoma is a brain neoplasm that is being recognized with increasing frequency. We discuss the radiographic findings in 14 pathologically proven cases. At angiography in nine cases, four showed mixed dural and pial vascular supply to the lesion. Early cortical venous drainage, irregular tumor vessels, and a prominent vascular stain with well-defined tumor margins were seen in the majority o...

Glioblastoma, the most frequent primary brain tumor and the most malignant neoplasm, can have the most heterogeneous morphological presentation. Along with classical morphological features, areas of oligodendroglial component and mesenchymal differentiation may be seen. The present case was a rare case of glioblastoma presenting with sarcomatous and oligodendroglial components. The case was dia...

Atypical teratoid/rhabdoid tumor of the central nervous system is a highly malignant neoplasm in infants and young children. We report a 6 year-old girl with atypical teratoid/rhabdoid tumor. Based on cerebrospinal fluid examination MRI scan and family history of tuberculosis; we diagnosed tuberculous meningitis. There was inadequate response to the antituberculosis therapy; so we performed ste...

Metastasis into a thyroid neoplasm-tumor-to-tumor metastasis-is exceedingly rare. We describe the 28th documented case of a tumor metastatic to a thyroid neoplasm and review the literature on tumor-to-tumor metastasis involving a thyroid neoplasm as recipient. All cases showed a recipient thyroid neoplasm with an abrupt transition to a morphologically distinct neoplasm. Metastasis into primary ...

We report a case of a supratentorial primitive neuroectodermal tumor (PNET) that occurred 12 years after cranial irradiation for a grade II astrocytoma. Neuroimaging was unable to distinguish between a recurrence of the original neoplasm and the development of a new, distinct entity. Pathologic review assisted by immunohistochemical staining, however, revealed a high-grade PNET. Although rare, ...

Choroid plexus papilloma (CPP) is a low-grade neoplasm of the choroid plexus that typically occurs in childhood and comprises under 1% of adult brain tumors. In this article, we report our experience delivering craniospinal irradiation (CSI) to a highly unusual case of disseminated CPP in an adult patient 8 years after an initial near total resection. The patient remains free of disease progres...

The typical CT characteristics of glioblastoma multiforme (GBM) are well known . Glioblastomas usually enlarge by infiltrating adjacent brain parenchyma, without affecting the overlying bone. We report an unusual case of a temporal lobe GBM that destroyed the bone of the middle fossa and subsequently infiltrated the temporalis muscle. The presence of bone destruction on CT suggested an extraaxi...

Colloid cysts are mucous-filled masses with an outer fibrous layer. These cysts are rare developmental malformation and not a true neoplasm. They usually found incidentally and are asymptomatic; but in some cases may associate with rapid neurologic deterioration, herniation, and sudden death. Recognition of this rare but important diagnosis may result in decreasing mortality. In this report, we...

This case report describes clinical, surgical, MR, and pathologic findings of an intraventricular fibroma, a rare, benign mesenchymal neoplasm. Relatively isointense with normal brain parenchyma on T1-weighted images, the tumor exhibited hyperintense signal on T2-weighted pulse sequences and enhanced intensely and homogeneously after intravenous administration of gadopentetate dimeglumine. Chor...