Three atrial natriuretic peptide (ANP) receptors, ANP(A), ANP(B), and ANP(C), have been identified in the heart, suggesting that natriuretic peptides may have direct effects on cardiac function. To characterize the possible role of atrial natriuretic peptide (ANP) in the regulation of its own secretion, we studied here the effects of ANP (greater affinity for ANP(A) than for ANP(B) receptors) a...

Objective: To evaluate the efficacy and safety of Shenfu injection in treatment septic cardiomyopathy. Methods: Literatures on for sepsis published from establishment each database to December 31, 2020, were searched by computer; Cochrane risk-of-bias tool was used evaluating quality literatures, Review Manager 5.4 software meta-analysis. Results: Twenty random controlled trials (RCTs) included...

Patients with unstable coronary artery disease (CAD), i.e., unstable angina or non-ST-elevation myocardial infarction, vary widely in clinical presentation, prognosis and response to treatment. To select appropriate therapy, early risk stratification has become increasingly important. This review focuses on the emerging role of natriuretic peptides in the early assessment of patients with unsta...

Abstract Introduction The objective of the present research was to evaluate possible association between N-terminal pro-brain type natriuretic peptide (NT-proBNP) levels and in-hospital mortality in coronavirus disease 2019 (COVID-19) pneumonia patients who did not have pre-existing heart failure (HF). Methods A total 137 consecutive without HF hospitalized due COVID-19 were enrolled into curre...

OBJECTIVES To evaluate the accuracy of B-type natriuretic peptide (BNP) and amino-terminal pro-brain natriuretic peptide (NT-proBNP) for the diagnosis of congestive heart failure (CHF) in dyspneic patients aged >or=85 years admitted to the Emergency Department (ED), and to define threshold values in this oldest-old population. DESIGN AND METHODS This study involved 210 oldest-old patients, an...

Aim: To investigate the changes of insulin resistance (IR), parameters arterial stiffness, concentrations N-terminal pro-brain natriuretic peptide (NT-proBNP), and echocardiographic in patients with cardiac autonomic neuropathy (CAN) type 2 diabetes mellitus (T2D). Methods: This study recruited 44 T2D (19 without CAN 25 CAN) 15 healthy volunteers. Arterial immunoreactive insulin, homeostasis mo...

      Kawasaki disease (KD) is characterized as the leading cause of acquired cardiac disease in children. Accurate and timely diagnosis of KD is of high importance for preventing its cardiac complications. However, diagnosis merely based on clinical findings has a number of challenges and, limitations. Therefore, researchers are investigating to find more object...

The clinical utility of plasma natriuretic peptide concentrations in dogs with right-sided congestive heart failure (CHF) remains unclear. We investigated whether plasma levels of atrial natriuretic peptide (ANP) and N-terminal pro B-type natriuretic peptide (NT-proBNP) are useful for assessing the congestive signs of right-sided heart failure in dogs. This retrospective study enrolled 16 healt...

BACKGROUND While the N-terminal pro-brain-type natriuretic peptide (NT-proBNP) at rest is known to be associated with prognosis in pulmonary arterial hypertension (PAH), it is unclear if the NT-proBNP response to exercise (ΔNT-proBNP) can contribute to a better assessment of disease severity. METHODS We investigated the association of NT-proBNP values at rest and during peak exercise with hem...

BACKGROUND Symptoms of breathlessness, fatigue, and ankle swelling are common in general practice but deciding which patients are likely to have heart failure is challenging. AIM To evaluate the performance of a clinical decision rule (CDR), with or without N-Terminal pro-B type natriuretic peptide (NT-proBNP) assay, for identifying heart failure. DESIGN AND SETTING Prospective, observation...