The inflammatory response is thought to be important for secondary damage following traumatic brain injury (TBI). The inducible nitric oxide synthase (iNOS) isoform is a mediator in inflammatory reactions and may catalyze substantial synthesis of NO in the injured brain. This study was undertaken to analyze neuronal degeneration and survival, cellular apoptosis and formation of nitrotyrosine fo...

Traumatic brain contusions have been associated with regional ischemia. We aimed to measure the effect of induced supra-normal values of cerebral perfusion pressure (CPP) on regional cerebral blood flow (rCBF) in the intracontusional low density area surrounding the contusional hemorrhagic core. In 7 severely head injured patients (GCS < or = 8) harbouring a contusion larger than 2 cm, the rCBF...

Introduction: Traumatic brain injury patients present in the emergency room with a variable conscious status depending upon severity of injury. The process aspiration starts from scene trauma as and chest have higher rates pneumonia.&#x0D; Materials Methods: We conducted prospective study to assess impact bronchoscopy lavage aggressive physiotherapy on Critical Pulmonary Infection Score Patient...

Approximately 1.7 million people sustain a traumatic brain injury (TBI) each year, with motor vehicle crash (MVC) representing the leading cause for TBI-related hospitalization. Subarachnoid hemorrhage (SAH), subdural hematoma (SDH), cerebral contusion, and diffuse axonal injury (DAI), are some of the most common and serious consequences of MVC-related TBI and are associated with high mortality...

Each patient presents a unique set of characteristics and challenges when it comes to acute cerebral ischemia resulting from craniocerebral injury. The aim this study is investigate the utilization Thiocetam as part comprehensive treatment approach for combat-related contusion assess therapeutic effects in patients with mild moderate closed combat trauma comparison standard basic therapy. Mater...

It remains unclear whether etanercept penetrates directly into the contused brain and improves the outcomes of TBI by attenuating brain contents of TNF- α and/or stimulating newly formed neurogenesis. Rats that sustained TBI are immediately treated with etanercept. Acute neurological and motor injury is assessed in all rats the day prior to and 7 days after surgery. The numbers of the colocaliz...

Persistent profound visual loss following contusion of the globe or ocular adnexae has been well documented, the visual loss being attributed to haemorrhage into, or contusion of, the optic nerve, or to interference with the blood supply of the eye. The patient described below presented after a contusion of the eye and orbit, with the clinical picture of ischaemic optic neuropathy presumably re...

Summary A 3‐year‐old Thoroughbred mare found recumbent in the field was referred for further assessment with suspicion of a skull fracture. Neurological examination identified compulsive tight circling to left, and hypermetria all four limbs. The obtunded, mild head tilt right, absent menace response right eye decreased facial sensation on right. Standing computed tomographic revealed subtle de...

PURPOSE Tljl study w designed LO obww the hema3ynwdc changea Md e?tdud th.9 therapsutie effed, of Compound AnLodinc, CA a,d Tolardne. TZL with rhsmphthdnw.qmphy.RQQ on cm&r conwdaa in rabh. METHODs 54 r~,108 eye4 (54 cyt4 with blunt tmwm * 2.8 lm4kx. S4 mntrdaterd eyes) we divided randomly itat4 d aroup8. Ihey awe -ei by ROQ before inhuy, &in 1.3 and ? &ya after inlay. M eontwd eyea uyrc treste...