نتایج جستجو برای: bradyporus latipes

تعداد نتایج: 1249  

2012
Masato KINOSHITA M. KINOSHITA

Recently, small model fish, medaka and zebrafish, have been casted a light on environmental science. Transgenic technique is a method that introduce exogenous gene into host genome and enables to generate unique model creature. Adapting transgenic technique on these fish, they become more powerful tool for evaluating aquatic contamination. Chemical analysis and in vitro bioassay, such as ELISA,...

2017
In-Seok Park Hyun Woo Gil Tae Ho Lee Yoon Kwon Nam Sang Gu Lim Dong Soo Kim

Optimum concentrations of anesthetic clove oil and anesthetic lidocaine-HCl were determined for a species of adult marine medaka, Oryzias dancena, over a range of salinity conditions, and investigated in a transport simulation experiment by analyzing various water and physiological parameters. Research indicated that the higher the concentration of anesthetic at each salinity, the shorter the a...

Journal: :Environmental toxicology and chemistry 2005
Susan C Tilton Christy M Foran William H Benson

Many biochemical endpoints currently are used to describe endocrine function in fish; however, the sensitivity of these parameters as biomarkers of impaired reproduction or sexual development is not well understood. In the present study, adult Japanese medaka (Oryzias latipes) were assessed for reproductive output and endocrine function, including circulating steroid concentrations, ex vivo ste...

2016
Jose Arturo Gutierrez-Triana Juan L Mateo David Ibberson Soojin Ryu Joachim Wittbrodt

DNA adenine methyltransferase identification (DamID) has emerged as an alternative method to profile protein-DNA interactions; however, critical issues limit its widespread applicability. Here, we present iDamIDseq, a protocol that improves specificity and sensitivity by inverting the steps DpnI-DpnII and adding steps that involve a phosphatase and exonuclease. To determine genome-wide protein-...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1999
W M Muir R D Howard

Widespread interest in producing transgenic organisms is balanced by concern over ecological hazards, such as species extinction if such organisms were to be released into nature. An ecological risk associated with the introduction of a transgenic organism is that the transgene, though rare, can spread in a natural population. An increase in transgene frequency is often assumed to be unlikely b...

Journal: :Genetics 2009
Vincent W Keng Barbara J Ryan Kirk J Wangensteen Darius Balciunas Christian Schmedt Stephen C Ekker David A Largaespada

Insertional mutagenesis screens play an integral part in the annotating of functional data for all sequenced genes in the postgenomic era. Chemical mutagenesis screens are highly efficient but identifying the causative gene can be a laborious task. Other mutagenesis platforms, such as transposable elements, have been successfully applied for insertional mutagenesis screens in both the mouse and...

2011
Daigo Inoue Joachim Wittbrodt

BACKGROUND For the detection and sub-cellular (co)-localization of proteins in the context of the tissue or organism immunostaining in whole mount preparations or on sections is still the best approach. So far, each antibody required its own fixation and antigen retrieval protocol so that optimizing immunostaining turned out to be tedious and time consuming. METHODOLOGY/PRINCIPAL FINDING Here...

Journal: :Biology letters 2010
Laura K Weir James W A Grant

Sperm limitation is widespread across many animal species. Several mechanisms of sperm allocation have been proposed, including optimal allocation according to clutch size and equal allocation across females. However, considerably less effort has been directed at investigating the behavioural signals associated with sperm limitation in males, which may include mating rate and the intensity of c...

2013
Jae-Gu Cho Kyung-Tae Kim Tae-Kwon Ryu Jae-woo Lee Ji-Eun Kim Jungkon Kim Byoung-Cheun Lee Eun-Hye Jo Junheon Yoon Ig-chun Eom Kyunghee Choi Pilje Kim

The developmental toxicity of silver nanoparticles (AgNPs) was investigated following exposure of Oryzias latipes (medaka) embryos to 0.1-1 mg/L of homogeneously dispersed AgNPs for 14 days. During this period, developmental endpoints, including lethality, heart rate, and hatching rate, were evaluated by microscopy for different stages of medaka embryonic development. To compare toxic sensitivi...

Journal: :Mechanisms of Development 2004
Harun Elmasri Christoph Winkler Daniel Liedtke Takao Sasado Chikako Morinaga Hiroshi Suwa Katsutoshi Niwa Thorsten Henrich Yukihiro Hirose Akihito Yasuoka Hiroki Yoda Tomomi Watanabe Tomonori Deguchi Norihisa Iwanami Sanae Kunimatsu Masakazu Osakada Felix Loosli Rebecca Quiring Matthias Carl Clemens Grabher Sylke Winkler Filippo Del Bene Joachim Wittbrodt Keiko Abe Yousuke Takahama Katsuhito Takahashi Toshiaki Katada Hiroshi Nishina Hisato Kondoh Makoto Furutani-Seiki

The metameric structure of the vertebrate trunk is generated by repeated formation of somites from the unsegmented presomitic mesoderm (PSM). We report the initial characterization of nine different mutants affecting segmentation that were isolated in a large-scale mutagenesis screen in Medaka (Oryzias latipes). Four mutants were identified that show a complete or partial absence of somites or ...

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