grasspea (lathyrus sativus) is a protein-rich forage legume that contains a neurotoxin (beta-odap) that causes severe malformation of the body’s extremities when eaten in large quantities. various low-toxin lines of grasspea have been developed to reduce the toxin’s concentration in the grain, i.e. to below the 0.2% critical value, but there are indications that zinc (zn) can also reduce the to...

abrin known as ribosome inactivating protein’s (rip) it is a high cytotoxic plant protein. high lethality and low cost and easy access to plant and seeds lead to this toxin used in crimes and terrorist acts. because obtaining purified toxins requires advanced laboratory equipment and complex procedures, so, it appears that the perpetrators of such crimes use crude extracts. as a result, remaini...

shiga toxin (stx) is the principal virulence factor of shigatoxigenic escherichia coli (stec), a food-born pathogen associated disease with uncomplicated diarrhea or the hemolytic-uremic syndrome. in this study, rabbit polyclonal anti recombinant a, b subunits of shiga toxin and holotoxin antisera were raised and employed for immunological purpose. by immunoblotting, these antisera recognized r...

UNLABELLED Clostridium perfringens epsilon toxin (ε-toxin) is responsible for a devastating multifocal central nervous system (CNS) white matter disease in ruminant animals. The mechanism by which ε-toxin causes white matter damage is poorly understood. In this study, we sought to determine the molecular and cellular mechanisms by which ε-toxin causes pathological changes to white matter. In pr...

In this study, mutant forms of Bacillus thuringiensis spp. israelensis (H14) were produced. These mutants were identified when the cells were cultured on chloramphenicol plates and stained with crystal violet. Protoplasts of the mutants were isolated by enzymatic digestion (lysozyme) of the cell walls at the presence of an osmotic stabilizer. The protoplasts were induced to fuse to each other i...

An atypical toxin variant of Clostridium botulinum (strain 657) was isolated from the feces of a 6-week-old female infant whose symptoms and clinical history were consistent with infant botulism. Toxin detected in the feces and the toxin produced by isolates from the feces and from two rectal swabs could be neutralized by type B botulinal antitoxin only at very high ratios of of antitoxin to to...

Fusarium is a fungus that is commonly found as saprophytes with parasitic life on some living organisms. Mycoprotein or fungus proteins with physical and chemical features are known as food in recent years. When they are involved in temperature and wet stress, release materials such as mycotoxins or fungus toxins remained in food. Zearalenone and dependent compounds have distinct role in many f...

Botulinum toxin (Botox) is a neurotoxin drug that used in wide range of cosmetic and treatment applications. This literature review provides an overview the mechanism its effects. The popularity usage has been tremendously increasing since it minimally invasive procedure. Application primarily utilized for purposes, to treat disorders, as surgery alternative. myths such frozen face have elabora...

Paralytic shellfish poisoning (PSP) is a human foodborne syndrome caused by the consumption of that accumulate paralytic toxins (PSTs, saxitoxin group). In PST-producing dinoflagellates such as Alexandrium spp., toxin synthesis encoded in nuclear genome via gene cluster ( sxt ). Toxin production supposedly associated with presence 4th domain sxtA sxtA4 ), one core genes PST cluster. It postulat...