A major problem remaining in the evaluation of boronated compounds for neutron capture therapy (NCT) is the need to know the intraor extracellular microdistribution of boron. This is a consequence of the short range of the '°B(n,a)7Lireaction products (-10 urn), such that biological efficacy is dependent upon intracellular distribution. In partic ular, if boron location is predominantly extrac...

Borocaptate sodium (Na2B12H11SH) is a potentially useful compound for boron neutron capture therapy of intracranial tumors. Tumor and normal tissue boron concentrations were evaluated in 30 dogs with naturally occurring intracranial tumors after i.v. borocaptate sodium infusion (55 mg boron/kg). Postmortem tissue boron concentrations were measured for three postinfusion time periods (2, 6, and ...

Boric acid and its less-known derivative lithium metaborate are inorganic acids used in a wide diverse array of industrial clinical applications. In particular, boric is accepted as natural antimicrobial agent due to activity on many different microbial species. We have examined the possible dependency metaborate-induced yeast toxicity deletion antioxidative CTT1, TRR2 GSH2 genes expressions ce...

Boron plays an important role in crop nutrition. Cauliflower expresses its sensitivity towards boron application which ultimately decides the potential of yield and quality curds. In this study, we presented assessment critical level soil concentration by graphical statistical procedures using cauliflower as a test crop. Thirty (30) samples collected from three rice growing sub-division Imphal-...

A profile of impurities in bortezomib anhydride, produced by a recently developed convergent technology, has been characterized. HPLC-MS analysis of the drug essence revealed three impurities: an epimer of bortezomib, resulting from partial racemization of l-phenylalanine's stereogenic center during the chemical synthesis, and two epimeric products of oxidative degradation of bortezomib, in whi...

As a result of the boron refining process, the Rio Tinto Borax site in California has experienced boron contamination, leading to desertification and the loss of local vegetation. Increasing industrial demand for the energy reduction ability of boron promotes continued mining. As such, the development of an effective and low-cost method for long-term reclamation is important. To establish this ...

azomethine-H methods are based on ABSTRACT photometry (1,9,33). AWPA A2-98 (1) This paper describes the development of a microsssay for boron and the application macroassay method has been used in of this microassay for evaluating leachability of boron by post-treatment of southern several studies to measure boron conpine with the calcium precipitating agent NHA (N'N-napthaloylhydroxylamine). T...

Here, we provide the data from a comparative proteomics approach used to investigate the response of boron (B)-tolerant 'Xuegan' (Citrus sinensis) and B-intolerant 'Sour pummelo' (Citrus grandis) leaves to B-toxicity. Using two-dimensional gel electrophoresis (2-DE) technique, we identified 50 and 45 protein species with a fold change of more than 1.5 and a P-value of less than 0.05 from B-toxi...

introduction: boron possesses widespread properties and is important for human and animal nutrition. since boron is rapidly bioavailable, the objective of the present study was to determine whether acute (hourly or daily), and weekly supplementationcould have any significant biological effects on the synthesis of steroids as well as inflammatory biomarkers. methods: eight male volunteers partic...

New and exciting developments in boron research in the past few years greatly contributed to better understanding of the role of boron in plants. Purification and identification of the first boron-polyol transport molecules resolved much of the controversy about boron phloem mobility. Isolation and characterization of the boron-polysaccharide complex from cell walls provided the first direct ev...