نتایج جستجو برای: bone induction
تعداد نتایج: 495870 فیلتر نتایج به سال:
Osteoblastic differentiation from human mesenchymal stem cell (hMSCs) is an important step of bone formation. We studied the in vitro induction of hMSCs by using strontium ranelate, a natural trace amount in water, food and human skeleton. The mRNA synthesis of various osteoblast specific genes was assessed by means of reverse transcription polymerase chain reaction (RT-PCR). In the hMSCs cultu...
In guided bone regeneration (GBR), a barrier membrane is applied to provide space for promote cell adhesion, proliferation, and by inducing migration the surface of bone-deficient site. We prepared non-woven absorbable GBR comprised copolymer L-lactic acid glycolic (PLLGA) using dry spinning method. A thin dense comprising unsintered hydroxyapatite (uHA) poly-L-lactic (PLLA) was used comparison...
objective(s): although many researchers have confirmed induction of germ cells from bone marrow mesenchymal stem cells (bmmscs), there are no reports that confirm spontaneous differentiation of germ cells from bmmscs. in this study, we have evaluated the effect of adult sertoli cell condition medium (sccm) as a mutative factor in the induction of germ cells from bmmscs. materials and methods: b...
The Wnt pathway plays a critical role in development and differentiation of many tissues, such as the gut, hair follicles, and bone. Increasing evidence indicates that Wnts may function as key regulators in osteogenic differentiation of mesenchymal stem cells and bone formation. Conversely, aberrant Wnt signaling is associated with many osteogenic pathologies. For example, genetic alterations i...
BACKGROUND CONTEXT The hyoid bone is used as a landmark in anterior upper cervical spine operations and is supposed to represent the level of C3 body. However, this correspondence between hyoid bone position and cervical level is not static and changes during surgery (extension after anesthesia). PURPOSE To find the cervical level corresponding to the position of hyoid bone before and after a...
The induction of ectopic bone formation has been described in a wide range of experimental systems. This lias emphasized the fact that undifferentiated osteogenic precursor cells persist in post foetal life after embryonic differentiation has ceased. A key observation in the studies on the transformation of these cells into osteoblasts was made by Urist [1965] when he discovered that the decalc...
which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. A 47-year-old woman visited our hospital complaining of recently developed back pain. Complete blood cell counts cells. Her bone marrow (A) (H&E, ×400) was packed with blasts, which were positive for CD34, CD19, CD20, CD10, and TdT. The diagnosis of precurso...
Zinc-containing tricalcium phosphate (Zn-TCP) was synthesized to investigate the role of zinc in osteoblastogenesis, osteoclastogenesis and in vivo bone induction in an ectopic implantation model. Zinc ions were readily released in the culture medium. Zn-TCP with the highest zinc content enhanced the alkaline phosphatase activity of human bone marrow stromal cells and tartrate-resistant acid ph...
background: in recent years, adipose tissue, due to the stem cells contained within, has found a new special place in laboratory and clinical applications. these adipose‑derived stem cells (adscs) have the same characteristics of bone marrow mesenchymal stem cells (bmscs). although bone marrow (bm) is not easily accessible and its procurements may be painful, most patients possess excess fat wh...
Synergistic effects of fibroblast growth factor-2 and bone morphogenetic protein-2 on bone induction
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