Atherosclerotic vascular calcification and bone mineral density (BMD) appear to mirror each other—less goes hand-in-hand with excess calcification—with plausible biological mechanisms explain this apparent paradox. But whether the vascular-bone relationship is an independent association or simply related ageing process shared risk factors has been unclear. In issue of Heart , Park colleagues1 i...

Osteoporosis is a metabolic disease characterized by low bone mass and microarchitectural deterioration of bone tissue, leading to enhanced bone fragility and a consequent increase in fracture risk. Bone fragility depends on bone density, turnover and microarchitectural features, such as relative trabecular volume, spacing, number and connectivity. Previous fragility fractures increase the frac...

Patients with COPD have high risk for osteoporosis and fractures. Hip and vertebral fractures might impair mobility, and vertebral fractures further reduce lung function. This review discusses the evidence of bone loss due to medical treatment opposed to disease severity and risk factors for COPD, and therapeutic options for the prevention and treatment of osteoporosis in these patients. A revi...

OBJECTIVE To evaluate the criteria for the prescription of oral bisphosphonates (OB) in a series of women with osteoporosis referred for tooth extraction. STUDY DESIGN The study included 38 postmenopausal women on treatment with OBs. The following variables were analysed: age, weight, height, type of OB and duration of treatment, bone densitometry and risk factors for osteoporosis. In additio...

I bone densitometry sources find extensive application in the diagnosis of osteoporosis by using single photon absorption (SPA) technique. Silver pellets of size ~ 2.5 mm (f) x 0.6 mm (l) were developed as base matrix for adsorption of I. Determination of specific surface area and pore size analysis of plain silver and palladium coated silver pellets was carried out. Experimental conditions for...

This study presents the outcome of osteoporosis treatment in a 29-year-old male patient with full-blown Touraine-Solente-Gole syndrome. His first DXA densitometry of the proximal femur demonstrated severe osteoporosis (BMD 0.628 g/cm(2); T-score -3.84 SD, Z-score -3.37 SD). Bisphosphonate treatment (alendronate 70 mg once weekly) produced considerable clinical improvement during a 36-month foll...