Background: Transfusion is the mainstay treatment of patients with thalassemia major and occasionally in thalassemia intermediate. Alloimmunization is an unwanted side effect of blood transfusion. The present study intended to determine the frequency of alloimmunization in patients with β- thalassemia major and thalassemia intermediate in Southwest Iran. Patients and Methods: This was a cross-...

Background: Patients with thalassemia major require frequent blood transfusions. Blood transfusion can lead to the adverse reactions. Reporting and evaluating the transfusion reactions are among the goals of implementing the hemovigilance system to improve blood recipients’ safety. This study aimed to compare the transfusion reactions in the thalassemia patients before and after implementation ...

background and aims: this study was the trends of hepatitis b infection among iranian blood donors which was analyzed in a period of 10 years. materials and methods: in a period of 10 years, from 2001 through 2010, a total of 16,264,830 donations from 30 regional and 35 local blood services were screened. all blood samples were tested for hepatitis b surface antigen (hbs ag) by commercial avail...

objective: because of the host immunological system response against the minor blood groups of donor, transfusion in some cases, especially for patients require repeated transfusions (such as people with thalassemia), can be considered as a significant problem.  a proposed way is coating the surface antigens on red blood cells (rbcs) by covalent binding of methoxy polyethylene glycol (mpeg). th...

Synonyms and related keywords: blood transfusions, blood products, acute hemolytic transfusion reactions, transfusion complications, blood product reactions, allergic transfusion reaction, blood type, circulatory volume overload, anaphylactic transfusion reaction, blood anaphylaxis, hemolytic reactions, allergic reactions, anaphylactic reaction, anaphylaxis, transfusion-related acute lung injur...

BACKGROUND Increased costs and mortality associated with inappropriate blood transfusions have led to investigations about blood request and blood transfusion techniques. We investigated the transfusion status in patients who underwent orthopedic surgery in Poursina Hospital (Rasht, Iran) to optimizing blood usage and determine if a scheduled transfusion program for every orthopedic surgery cou...

background: host immune system response against blood group antigens is a major problem in blood transfusions, especially forthalassemic patients. thus, an approach was proposed coating the red blood cell (rbc) surface by polyethylene glycol.objectives: this study aimed to obtain the optimal simultaneous camouflge of the major and minor antigens by activated methoxypolyethylene glycol (mpeg) wi...

an estimated 150-200 million people worldwide are infected with hepatitis c. prevalence is higher in some countries in asia and africa. only limited information about the epidemiology of hepatitis c virus (hcv) infection especially in females is available. the aim of this study is to determine the prevalence of anti-hcv antibodies and the possible factors for transmission in the female populati...