Experimental studies indicate low revascularization of intraportally transplanted islets. This study aimed to quantify, for the first time, the blood perfusion of intrahepatically transplanted islets and elucidate necessary factors for proper islet graft revascularization at this site. Yellow chameleon protein 3.0 islets expressing fluorescent protein in all cells were transplanted. Graft blood...

Methods Longitudinal prospective analysis of 38 patients with aSAH. Inclusion: age 21-75 years, spontaneous aneurysm rupture, Fisher grade >1 and/or Hunt and Hess grade (HH) >2. Exclusion: traumatic SAH, recent myocardial dysfunction. Daily averages of systemic (systolic blood pressure [SBP], diastolic blood pressure [DBP], mean arterial blood pressure [MAP], heart rate [HR]) and cerebral (cere...

BACKGROUND During surgery, circulation changes in the deep inferior epigastric perforator free flap (DIEP). Although blood flow is an important parameter for surgical outcome, little research has been performed on this topic, especially during the process of transplantation. This study examined the pattern of perfusion of DIEP flaps over time. METHODS In all, 16 flaps were studied in 14 DIEP ...

A critical indicator of tissue viability and function is blood delivery to the capillary bed (referred to as perfusion or tissue/capillary blood flow), so the measurement of this process has been pursued by many MR scientists. Perfusion MRI is currently an effective tool to non-invasively quantify cerebral blood flow (CBF) and to easily obtain its relative change due to neural activity or other...

Introduction The pathophysiology of chest pain in patients with Syndrome X remains controversial. Previous studies using nuclear techniques or CMR to assess myocardial perfusion have shown conflicting results. Advances in perfusion imaging with CMR now enable absolute quantification of regional myocardial blood flow. Furthermore, blood oxygenation level-dependent (BOLD) CMR provides the unprece...

ASL fMRI data provides a quantitative measure of blood perfusion, that can be correlated to neuronal activation. In contrast to BOLD measure, it is a direct measure of cerebral blood flow. However, ASL data has a lower SNR and resolution so that the recovery of the perfusion response of interest suffers from the contamination by a stronger BOLD component in the ASL signal. In this work we consi...

Objective Although recent advances in pulmonary valve replacement have enabled excellent hemodynamics, infective endocarditis remains a serious complication, particularly for implanted bovine jugular vein (BJV) conduits. Methods We investigated contributions by platelets and plasma fibrinogen to initiation on various grafts used replacement. Thus, adherence of Staphylococcus aureus 5 graft tiss...

Spontaneous Intracranial Hypotension (SIH) is usually due to cerebrospinal fluid (CSF) leak, resulting in loss of CSF volume. Posterior reversible encephalopathy syndrome (PRES) the inability posterior circulation brain autoregulate response significant variation blood pressure. Altered perfusion with associated blood-brain barrier disruption may lead vasogenic edema, without infarction, common...