Recent studies have demonstrated that band 3 carries antigens of the Diego blood group system and have elucidated the molecular basis of several previously unassigned low incidence and high incidence antigens. Because the available serological data suggested that band 3 may carry additional low incidence blood group antigens, we screened band 3 genomic DNA encoding the membrane domain of band 3...

Recent studies have demonstrated that band 3 carries antigens of the Diego blood group system and have elucidated the molecular basis of several previously unassigned low incidence and high incidence antigens. Because the available serological data suggested that band 3 may carry additional low incidence blood group antigens, we screened band 3 genomic DNA encoding the membrane domain of band 3...

Gastric-mucosal glycoproteins of sheep have been shown to express the blood-group-I and -i antigens. The highest blood-group-I activities were found in glycoproteins lacking in blood-group-A and -H activities. In antigenically very active glycoprotein preparations, approx. 25% of the macromolecules expressed various blood-group-I and -i antigens, and these could be enriched by affinity chromato...

background: host immune system response against blood group antigens is a major problem in blood transfusions, especially forthalassemic patients. thus, an approach was proposed coating the red blood cell (rbc) surface by polyethylene glycol.objectives: this study aimed to obtain the optimal simultaneous camouflge of the major and minor antigens by activated methoxypolyethylene glycol (mpeg) wi...

The distribution of histo-blood group A type 1, 2 and 3 antigens was investigated using immunohistochemistry in normal human skin and extramammary Paget's disease (EMPD). We used monoclonal antibodies (mAbs) Bioclone-A (BA) and AR-1, which react with histo-blood group A type 1/2, and type 3 antigens, respectively. We found that A type 1, 2 and 3 antigens were expressed in the upper layer of the...

the frequencies of the different blood group antigens vary sigBlood group antigens are polymorphisms of proteins and carbohydrates on the surface of red blood cells (RBC) with the distribution of alleles varying between different ethnic groups and populations. By using the genetic information provided by the human genome project, the molecular basis of most blood group genes encoding blood grou...