We compare experimental melting curves of short heterogeneous DNA oligomers with theoretical curves derived from statistical mechanics. Partition functions are computed with the one-dimensional Peyrard-Bishop (PB) Hamiltonian, already used in the study of the melting of long DNA chains. Working with short chains we take into account, in the computations, not only the breaking of the interstrand...

AIM To compare the efficacy, safety, and patient's perception of two prostaglandin E2 application methods for induction of labour. METHOD Above 36th weeks of gestation, all women, who were admitted to hospital for induction of labour, were prospectively randomised to intravaginal 1 mg or intracervical 0.5 mg irrespective of cervical Bishop score. The main outcome variables were induction-to-d...

Background: The procedure of choice in the surgical treatment of cubital tunnel syndrome remains controversial. The aim of this study is to report the results of simple decompression and decompression with anterior subcutaneous transposition. Methods: A retrospective review (July 2002–January 2007) using the Bishop Score to assess outcome. A total of 102 procedures (91 patients, 11 bilateral) w...

OBJECTIVES To compare the efficacy of labour induction using sublingual misoprostol versus combined artificial rupture of membranes and oxytocin infusion for nulliparous women with a favourable cervix at term. DESIGN Open randomised controlled trial. SETTING Regional hospital, Hong Kong. PATIENTS Fifty nulliparous women with a favourable cervix (Bishop score 6 or more) at term and indicat...

OBJECTIVE This study aimed to determine the optimal Foley catheter balloon volume (30-mL vs. 80-mL) and the maximum time for cervical ripening (12 hours vs. 24 hours) to improve vaginal delivery rate within 24 hours of induction. METHODS We conducted an open-label, randomized controlled trial in a teaching hospital in China. Women with a term singleton pregnancy, cephalic presentation, intact...

background: we sought to compare the effectiveness and safety of sublingual versus vaginal misoprostol for the termination of pregnancy with a live full-term fetus. methods: this randomized, triple-blind, placebo-controlled clinical trial was performed on 200 primiparous women with normal, singleton, full-term pregnancies candidated for the induction of labor. sublingual and vaginal tablets con...

OBJECTIVE To quantify the risk and risk factors for cesarean delivery associated with medical and elective induction of labor in nulliparous women. METHODS A prospective cohort study was performed in nulliparous women at term with vertex singleton gestations who had labor induced at 2 obstetrical centers. Medical and elective indications and Bishop scores were recorded before labor induction....

Background Matrix metalloproteinase (MMPs) play an important role in development of female genital cancers and metastasis. The aim this study was to analyze expression levels MMP2 various grades cervical intraepithelial neoplasia (CIN) squamous cell carcinoma (SCC) cervix its association with clinicopathological variables. Patients methods This prospective carried out a tertiary care center Nor...