BACKGROUND Nonclinical studies indicate that the hormone relaxin is a good candidate for a safe cervical ripening agent that does not cause uterine contractions. METHODS This Phase II study (conducted November 2, 2005-October 20, 2006) was a randomised, double blind, placebo controlled trial testing 24-h intravenous infusion of serelaxin (recombinant human relaxin) or placebo for cervical rip...

Abstract Robert Burns’s song editor George Thomson (1757–1851) issued the poet’s cantata ‘Love and Liberty’, also known as ‘The Jolly Beggars’, for first time with music in 1818 (a setting of text narrator, solo singers, choir, piano trio). The musical score was by London theatre composer Sir Henry Bishop edited line his strict policy decency politeness. This essay tracks Thomson’s editorial cu...

Background: An increasing success in induction of labor and subsequent termination of pregnancy in presence of unfavorable cervix requires cervical ripening in order to reduce complications and to diminish the rate of cesarean sections as well as the duration of labor.  However, there is no consensus on the efficiency of conventional methods for cervical ripening. Objective: To determine and co...

Objective: The aim of this study was to investigate the effect of parity on cervical ripening and labor induction with intra-vaginal slow-release dinoprostone and to determine the safety and efficacy of this medication in a tertiary referral center. Methods: The medical records of 2090 pregnant women who underwent cervical ripening and induction of labor with Dinoprostone between January 2007 a...

OBJECTIVES To examine the value of pre-induction sonographic assessment of cervical length, posterior cervical angle and occipital position in the prediction of the induction-to-delivery interval within 24 h, the likelihood of vaginal delivery within 24 h, the likelihood of Cesarean section and to compare sonographic assessment with the Bishop score. METHODS In 604 singleton pregnancies, indu...