نتایج جستجو برای: biomimetic synthesis

تعداد نتایج: 416494  

2015
Yogesh K. Murugesan Damiano Pasini Alejandro D. Rey

This review on self-assembly in biological fi brous composites presents theory and simulation to elucidate the principles and mechanisms that govern the thermodynamics, material science, and rheology of biological anisotropic soft matter that are involved in the growth/self-assembly/material processing of these materials. Plant cell wall, a multi-layered biological fi brous composite, is presen...

Journal: :Journal of the American Chemical Society 2019

2011
Huimin Zhao

B generally refers to the use of enzymes or whole cells as catalysts for synthetic chemistry. Because of its connection with reduced energy consumption, greenhouse gas emissions, and waste generation, biocatalysis is increasingly used in pharmaceutical, chemical, food, energy, and agricultural industries. Compared to chemical catalysis, one of the biggest advantages of biocatalysis is that bioc...

Journal: :Chemistry, an Asian journal 2012
Kyoungmok Kim Takahiro Matsumoto Andrew Robertson Hidetaka Nakai Seiji Ogo

Herein, we report a [NiRu] biomimetic system for O(2)-tolerant [NiFe]hydrogenases and demonstrate that electron donation to the [NiRu] center can switch the system between the activation of H(2) and O(2) through simple ligand effects by using hexamethylbenzene and pentamethylcyclopentadienyl ligands, respectively. Furthermore, we present the synthesis and direct observations of a [NiRu]-peroxo ...

2015
Juan D. Guzman Thomas Pesnot Diana A. Barrera Heledd M. Davies Eleanor McMahon Dimitrios Evangelopoulos Parisa N. Mortazavi Tulika Munshi Arundhati Maitra Eleanor D. Lamming Richard Angell Markus C. Gershater Joanna M. Redmond Deborah Needham John M. Ward Luis E. Cuca Helen C. Hailes Sanjib Bhakta

OBJECTIVES (S)-Leucoxine, isolated from the Colombian Lauraceae tree Rhodostemonodaphne crenaticupula Madriñan, was found to inhibit the growth of Mycobacterium tuberculosis H37Rv. A biomimetic approach for the chemical synthesis of a wide array of 1-substituted tetrahydroisoquinolines was undertaken with the aim of elucidating a common pharmacophore for these compounds with novel mode(s) of an...

Journal: :Angewandte Chemie 2014
Jianguang Han Xia Li Yong Guan Wenjun Zhao William D Wulff Xiaoguang Lei

The first enantioselective total syntheses of prenylflavonoid Diels-Alder natural products (-)-kuwanon I, (+)-kuwanon J, (-)-brosimone A, and (-)-brosimone B have been accomplished from a common intermediate based on a concise synthetic strategy. Key elements of the synthesis include a biosynthesis-inspired asymmetric Diels-Alder cycloaddition mediated by a chiral ligand/boron Lewis acid, as we...

2013
Daniel Fürniss Timo Mack Frank Hahn Sidonie B L Vollrath Katarzyna Koroniak Ute Schepers Stefan Bräse

Sugar moieties are present in a wide range of bioactive molecules. Thus, having versatile and fast methods for the decoration of biomimetic molecules with sugars is of fundamental importance. The glycosylation of peptoids and polyamines as examples of such biomimetic molecules is reported here. The method uses Cu-catalyzed azide alkyne cycloaddition to promote the reaction of azidosugars with e...

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