Pyridazinone Herbicides, Carotenoids, Fluorescence Spectrum The effects o f three differently substituted pyridazinone herbicides on the accumulation o f photosynthetic pigments and on the fluorescence properties o f greening barley leaves were studied. The two trifluoro-methyl derivatives, SAN 6706 and 9789 caused inhibition in the accumulation o f carotenes only after the First 24 h of greeni...

This article describes the utility of certain readily accessible, ring-fused gem-dihalogenocyclopropanes as building blocks for the synthesis of heterocyclic and biologically active compounds.

Optically active highly functionalized 3,4-dihydropyridin-2-ones were synthesized by N-heterocyclic carbene-catalyzed [4+2] enantioselective cycloaddition of ketenes and 1-azadienes.

Objective: The aim of the work was to develop effective methods for synthesis promising heterocyclic systems based on pyrrole and 1,2,4-triazole. In process realizing this aim, 10 new S-alkyl 4-(4-chlorophenyl)-5-(pyrrole-2-yl)-1,2,4-triazole-3-thiol derivatives were synthesized. Material Method: Chemical structures synthesized compounds characterized with elemental analysis, 1H-NMR, LC-MS tech...

The title compound, C(30)H(30)N(4)O(2), has a non-planar conformation, the dihedral angles formed by the pyridazinone ring plane and the three phenyl rings being 54.61 (7), 51.10 (7) and 59.53 (8)°. The piperazine ring adopts a chair conformation. Inter- and intra-molecular C-H⋯O contacts are found in the crystal structure and these consolidate the three-dimensional packing.

Levosimendan is a pyridazinone-dinitrile derivative with positive inotropic and vasodilatory effects that has beneficial effects on myocardial performance. In previous randomized studies levosimendan improved hemodynamics and clinical course, but its effect on prognosis is still unclear. This important issue has limited its use. Although primarily used in the management of acute heart failure s...

Heterocyclic compounds make a very important branch of organic chemistry, and it has always been an interesting area study in medical chemistry. They are present variety drugs, vitamins biologically active compounds. Over two decades, 1,3,4-oxadiazoles have interest to chemists owing their diverse therapeutic potential; the studies focus mainly on principles combinatorial chemistry with broad s...

Recently, heterocyclic compounds analogues and their derivatives have attracted strong interest in medicinal chemistry due to their biological and pharmacological properties. The small and simple thiadiazole nucleus possesses numerous biological properties like antitumor, antimicrobial, anti-inflammatory, anticonvulsant, and antidiabetic activities. These activities are also possessed by its su...