Renal failure is commonly accompanied by psychological distress compounding to mental health conditions such as anxiety and depression. Common risk factors towards the development of disorders in people with renal include need attend regular hemodialysis session burden related complications. A growing body evidence has elucidated biochemical immunological underpinnings context failure. This kno...

The current review describes inherited platelet disorders, illustrates their clinical phenotype and molecular genetic defects. Platelets are the key molecules mediating haemostasis via adhesion, activation and clot formation at the site of injury. The inherited platelet disorders can be classified according to their platelet defects: receptor/cytoskeleton defects, secretion disorder, and signal...

LABORATORY DATA biochemical markers metabolic defect chromosomal assignment chromosome 5q localization gene, structural-functional anomalies CNCG tissue cyclic nucleotide gated channel photoreceptor gene analysis-DNA analysis Marineso-Sjogren syndrome ( MSS) gene chr.5q31 pituitary hormones, modified functions follicle-stimulating hormone, gonadotrophin (FSH) , high levels luteinizing hormone, ...

Dementia disorders are characterized by clinicopathological criteria. Molecular understandings of these disorders, based on immunohistochemical studies, biochemical investigations, genetic approaches, and animal models, have resulted in advances in diagnosis. Likewise, translational research has allowed us to apply our increasing basic scientific knowledge of neurodegeneration to the rational d...

The main purpose of newborn screening is to diagnose genetic, metabolic, and other inherited disorders, at their earliest to start treatment before the clinical manifestations become evident. Understanding and tracing the biochemical data obtained from tandem mass spectrometry is vital for early diagnosis of metabolic diseases associated with such disorders. Accordingly, it is important to focu...