background: considering the increasing rates of early hospital discharge and kernicterus in healthy full term newborns, timely identification of neonates at risk of severe hyperbilirubinemia is of great significance. the aim of this study was to investigate the predictive value of umbilical cord serum (ucs) bilirubin level for subsequent hyperbilirubinemia. moreover, we compared the predictive ...

The methanol extract of Bauhinia racemosa Lam. (Caesalpiniaceae) stem bark was investigated for the antioxidant and hepatoprotective effects in Wistar albino rats. Different groups of animals were administered with paracetamol (500 mg/kg, (p.o.) once in a day for 7 days) and carbon tetrachloride (CCl4) (30 % CCl4, 1 ml/kg b.wt. in liquid paraffin 3 doses (i.p.) at 72 h interval). The methanol e...

introduction: one of the most common pathologies in neonates is hyperbilirubinemia, which is a good marker for damage to the central nervous system. the sensitivity of the auditory system to bilirubin has been previously documented, with much discrepancy in its effects on auditory brainstem response results. thus the objective of this study was to evaluate the effects of hyperbilirubinemia on a...

BACKGROUND Elevated serum bilirubin concentrations protect against atherosclerotic diseases; however, it is not clear whether higher serum bilirubin concentrations in physiological ranges work in favor of the cardiovascular system in younger persons with no cardiovascular risk factors. Accordingly, we investigated the effects of high, intermediate, and low serum bilirubin concentrations on coro...

Obesity can cause insulin resistance and type 2 diabetes. Moderate elevations in bilirubin levels have anti-diabetic effects. This study is aimed at determining the mechanisms by which bilirubin treatment reduces obesity and insulin resistance in a diet-induced obesity (DIO) mouse model. DIO mice were treated with bilirubin or vehicle for 14 days. Body weights, plasma glucose, and insulin toler...

the present study was carried out to evaluate the hepatoprotective and antioxidant effect of the methanol extract of eupatorium ayapana (meea) (family- asteraceae) leaves in wistar albino rats. the different groups of animals were administered with carbon tetrachloride (ccl4) at 72 h interval.  the meea at 100, 200 and 300 mg/kg and silymarin 25 mg/kg were administered to the ccl4 treated rats....

The hepato-protective effect of Telfaria occidentalis leaves supplementation on paracetamol induced liver toxicity in wistar rats was investigated. A total forty Wistar (female and male) weighing between 150-250g were selected for the study. animals randomly divided into four groups five each. Animals group 1 2 received standard chow only while 3 4 5% 10% T. their feed respectively six weeks. G...