Bovine herpesvirus 5 (BHV-5) is a neurovirulent alphaherpesvirus that causes fatal encephalitis in calves. In a rabbit model, the virus invades the central nervous system (CNS) anterogradely from the olfactory mucosa following intranasal infection. In addition to glycoproteins E and I (gE and gI, respectively), Us9 and its homologue in alphaherpesviruses are necessary for the viral anterograde ...

Bovine herpesvirus 1 (BHV-1) is an important pathogen of cattle and infection is usually initiated via the ocular or nasal cavity. After acute infection, the primary site for BHV-1 latency is sensory neurons in the trigeminal ganglia (TG). Reactivation from latency occurs sporadically, resulting in virus shedding and transmission to uninfected cattle. The only abundant viral transcript expresse...

Aim: Four viral pathogens, bovine viral diarrhea virus (BVDV), and bovine herpes virus type 1 (BHV-1), bovine parainfluenza type 3 virus (PI-3V), bovine respiratory syncytial virus (BRSV) are mainly associated with bovine respiratory diseases that cause major economic losses in the dairy cattle industry. This study aimed to document exposure of cattle in Saudi Arabia to infectious BVDV, BHV-1, ...

a cross-sectional study with a random cluster sampling design was carried out to estimate the seroprevalence of bovine herpesvirus type 1 (bhv-1) in non-vaccinated dairy herds in hamedan province, west of iran. simple random sampling was used for selection of cattle in each herd. informative data about each herd and selected animals were recorded by the farm manager in a provided questionnaire....

Sera from 221 cattle were collected in 25 farms in Morocco to investigate the evidence and circulation of some of the main bovine abortive agents in the dairy cattle farming, where abortions are often reported. All sera were examined for brucellosis, 176 for neosporosis, 88 for leptospirosis, and 42 for Bovine viral diarrhoea (BVD/MD), Bovine Herpesvirus 1 (BHV-1) (Infectious bovine rhinotrache...

The performance of a live marker vaccine for bovine herpesvirus type 1 (bhv-1) was studied in the field in three European Union countries with different farming conditions. The progress in the eradication of the virus was followed in a large herd in Germany and one in Italy, and a major serological survey involving 147 farms was conducted in Hungary. Commercial batches of the same vaccine were ...

In the course of the study 199 blood samples from sheep and goats were tested. They were collected from 4 mixed herds, situated in 4 different settlements, divided in two regions (two settlements in each). The sera were tested for presence of virus-neutralizing antibodies against Parainfluenza-3 Virus (PI-3), Bovine Viral Diarrhea Virus (BVDV) and Bovine Herpesvirus -1 (BHV-1); they were also t...

Serological survey on the occurrence of alpha-herpesvirus and pestivirus infections in the population of European bison in the Bialowieza Primeval Forest was conducted. Sera from 40 randomly selected individuals were tested using two commercial IDEXX ELISA tests. The study design allowed excluding or confirming the infection with the probability of 95% and at the expected prevalence of 30%. No ...

This study aimed the in vitro growth characterization of a previously constructed Brazilian bovine herpesvirus 1.2a with a deletion in the glycoprotein E gene (BHV-1.2a gE). The plaque sizes, penetration and growth kinetics of the Brazilian BHV-1.2a gE were studied and compared with the parental virus, as well as with a BHV-1.1 gE recombinant derived from an European BHV-1.1 strain. No statisti...