نتایج جستجو برای: bfi

تعداد نتایج: 418  

Journal: :Majalah Ilmiah Methoda 2022

Hydrocephalus is a complex disorder of the formation, flow, and absorption cerebrospinal fluid (CSF), characterized by increased intracranial pressure, pathological dilatation cerebral ventricles, excessive accumulation CSF. This study describes correlation hydrocephalus degrees in children aged 0-12 with clinical manifestation through head CT scan to measure degree mild, moderate, severe using...

2012
Sam H Ahmedzai Friedemann Nauck Gil Bar-Sela Björn Bosse Petra Leyendecker Michael Hopp

OBJECTIVE An examination of whether oxycodone/naloxone prolonged-release tablets (OXN PR) can improve constipation and maintain analgesia, compared with oxycodone prolonged-release tablets (OxyPR) in patients with moderate/severe cancer pain. METHODS Randomized, double-blind, active-controlled, double-dummy, parallel-group study in which 185 patients were randomized to receive up to 120 mg/da...

2016
Sarah Kim Woo Kyung Bae Ju Young Kim Mijee Jang Jeong Hyun Kim Hyun Hee Noh

The Schedule of Fatigue and Anergy/General Physician (SOFA/GP) was developed to screen for prolonged fatigue in the primary care setting. We aimed to evaluate the reliability and validity of the Korean version of the SOFA/GP (SOFA/GP-K), which is adapted from the original English version. We performed translation and back translation, and after conducting a pilot study, we tested the final vers...

2015
Elliot Max Tucker-Drob Kathryn Paige Harden David M. Buss Frank Dwight Mann Rachel Polk Jonathon Flores Daniel Briley Natalie Kretsch Marie Carlson Amanda Cheung Megan Patterson Andrew Grotzinger

Callous-unemotional (CU) traits, such as lacking empathy and emotional insensitivity, predict the onset, severity and persistence of antisocial behavior. CU traits are heritable, and genetic influences on CU traits contribute to antisocial behavior. This study examines genetic overlap between CU traits and general domains of personality. We measured CU traits using the Inventory of Callous and ...

Journal: :Bioorganic & medicinal chemistry 2010
Gianfabio Giorgioni Dario Ambrosini Cristian Vesprini Alan Hudson Cinzia Nasuti Antonio Di Stefano Piera Sozio Osele Ciampi Barbara Costa Claudia Martini Antonio Carrieri Giuseppe Carbonara Christoph Enzensperger Maria Pigini

Based on the well known biological versatility of the imidazoline nucleus, we prepared the novel derivatives 3a-k inspired by 2-BFI scaffold to assess imidazoline molecules as D(2)-like dopamine receptor ligands. Conservative chemical modifications of the lead structure, such as the introduction of an hydroxy group in the aromatic ring alone or associated with N-benzyl substitution, provided pa...

Journal: :Grundwasser 2022

Zusammenfassung Die Grundwasserneubildung in Festgesteinsbereichen ist aufgrund der hydrogeologischen Eigenschaften Gesteine im Allgemeinen geringer als den Porengrundwasserleitern Lockergesteine. Durch das Zusammenspiel dieser mit Topographie Mittelgebirgslandschaften Niedersachsens, findet dort neben auch ein signifikanter Zwischenabfluss statt. Methodisch können Wasserhaushaltsmodellen Rahme...

Journal: :Water 2021

The Sor and Gebba watershed has undergone several natural anthropogenic changes, as evidenced by the physical alterations artificial mismanagement of water resources in watershed. These situations alter underground storage aquifer contribution to streams. Thus, understanding baseflow enables us identify groundwater system potential dynamicity. main objective this research is estimate using hydr...

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