The leaves of Beilschmiedia brevipes provided a new benzylisoquinoline alkaloid: (6,7-dimethoxy-4-methylisoquinolinyl)-(4'-methoxyphenyl)-methanone (1) and O,O-dimethylannocherin A (2), a new natural compound which has been synthesized before. Complete 1H- and 13C-NMR data of both compounds were reported. The structures were established through various spectroscopic methods notably 1D- and 2D-N...

amaryllidaceae is a well-known family for its high alkaloidal content. these alkaloids comprise a unique group of bases that have been found to occur in this family. the amaryllidaceae alkaloids represent a large and still expanding group of isoquinoline alkaloids, the majority of which are not known to occur in any other family of plants this article reports on the phytochemical investigation ...

Noscapine is a benzylisoquinoline alkaloid produced in opium poppy (Papaver somniferum) and other members of the Papaveraceae. It has been used as a cough suppressant and more recently was shown to possess anticancer activity. However, the biosynthesis of noscapine in opium poppy has not been established. A proposed pathway leading from (S)-reticuline to noscapine includes (S)scoulerine, (S)-ca...

Tyrosine aminotransferase (TyrAT) catalyzes the transamination of L-Tyr and α-ketoglutarate, yielding 4-hydroxyphenylpyruvic acid and L-glutamate. The decarboxylation product of 4-hydroxyphenylpyruvic acid, 4-hydroxyphenylacetaldehyde, is a precursor to a large and diverse group of natural products known collectively as benzylisoquinoline alkaloids (BIAs). We have isolated and characterized a T...

Noscapine is a benzylisoquinoline alkaloid produced in opium poppy (Papaver somniferum) and other members of the Papaveraceae. It has been used as a cough suppressant and more recently was shown to possess anticancer activity. However, the biosynthesis of noscapine in opium poppy has not been established. A proposed pathway leading from (S)-reticuline to noscapine includes (S)-scoulerine, (S)-c...

The unique polycyclic fused ring systems of Daphniphyllum alkaloids, along with their extensive bioactivities, make this family of alkaloids especially attractive targets for total synthesis and biogenetic studies. Successive discoveries of new alkaloids with unprecedented skeletons have made a great contribution to structural diversities of alkaloids elaborated by plants of the genus Daphniphy...

background & aim: a. belladonna (family: solanaceae) is one of important pharmaceutical plants which contain tropane ‎alkaloids. tropane alkaloids are distinct group of secondary metabolites of the ‎solanaceae family.  the most important alkaloids of a. belladonna are atropine and hyoscine that are used extensively because of their medicinal properties. therefore identification and ‎determi...

papaver pseudo-orientale population tarom was shown to contain two major alkaloids, isothebaine (0.65%), orientalidine (0.15%) and four minor alkaloids, bracteoline, mecambridine, or and a novel alkaloid, nor-methyl or .

WITTERS, WELDON L. Extraction and identification of clavine and lysergic acid alkaloids from morning glories. Ohio J. Sci. 75(4): 198, 1975. Seeds from three varieties of Ipomoea grown in Ohio were examined for clavine and lysergic acid alkaloids. Three systems of extraction of ergoline alkaloids were compared with the ammonium hydroxide-methanol-chloroform method proving superior to the others...