The tin(IV) atom in the title compound, [Sn(C(8)H(9))(2)Cl(2)(C(12)H(8)N(2))], is chelated by the N-heterocycle and bonded to two C atoms and two chloride ions in an SnC(2)Cl(2)N(2) octa-hedral coordination environment with the C atoms trans to each other. The dihedral angles between the heterocycle ring system and the benzene rings of the 4-methyl-benzyl groups are 21.20 (12) and 28.71 (11)°.

Based on ab initio calculated results, a new mechanism is proposed that intramolecular hydrogen atom transfer may occur Ž . during the photodissociation of o-chlorotoluene at 266 nm. This mechanism is different from the general suggestion, i.e. 1 Ž . Ž . Ž . Ž . o-chlorotoluene S TMo-chlorotoluene T TMClqo-tolylTMbenzylqCl. Our suggestion is 2 o-chlorotoluene S TMo1 1 1 Ž . Ž . Ž . chlorotoluen...

A simple synthesis of sulfonamides 4-22 as novel histone deacetylase (HDAC) inhibitors is described. The key synthetic strategies involve N-sulfonylation of L-proline benzyl ester hydrochloride (2) and coupling reaction of N-sulfonyl chloride 3 with amines in high yields. It was found that several compounds showed good cellular potency with the most potent compound 20 exhibiting an IC50 = 2.8 m...

The title compound, C(11)H(14)Cl(2)O, was synthesized by the reaction of a dichloro-methane solution of (R)-carvone and potassium tert-butano-late in the presence of a catalytic amount of benzyl-triethyl-ammonium chloride in chloro-form. The cyclo-hexene ring adopts a half-boat conformation. The cyclo-propyl ring is unsymmetrical, the shortest C-C bond being distal to the alkyl-substituted C at...

The title compound, C(34)H(36)Cl(2)O(7), is a by-product from the reaction of 4-chloro-benzyl-zinc chloride with 3,4,5-trimeth-oxy-benzaldehyde. In each of the two 1,2-diphenyl-ethyl moieties, the two benzene rings are arranged in a trans conformation and make C(ar)-C-C-C(ar) torsion angles of 163.64 (19) and 174.43 (18)°. The crystal structure is stabilized by van der Waals inter-actions only.

A proximity effect in arene ^-complex formation from the reaction system of an aryl G r i g n a r d reagent and anhydrous chromic chloride was investigated. The yields of arene ^-complexes and any accompanying reaction products were compared by the systematic variation of the aryl G r i g n a r d reagent employed. Phenyl G r i g n a r d gave the best yield of jr-complex followed by the benzyl, ...

The title compound, C(29)H(35)N(3)O(4), was obtained by the reaction of (2S,4S,5S)-tert-butyl N-(4-amino-1-benzyl-3-hydr-oxy-5-phenyl-pent-yl)carbamate and picolinic acid using oxalyl chloride as a chlorinating reagent to activate the carboxyl group. In the crystal structure there are two mol-ecules in the asymmetric unit, which are aligned edge-to-face. In one mol-ecule, the pyridyl ring forms...