Series of new thirteen annulated heterocyclic were prepared and screened for their antioxidant activities. The ethyl-4(2-cyanoacetamido)benzoate as a multifunctional component which possess both electrophilic nucleophilic centers that utilized in organic synthesis different candidates. These compounds studied antioxidants at concentrations based on DPPH ABTS assays using ascorbic acid standard ...

Interactions between steroids and the nicotinic acetylcholine receptor (AChR) have been studied in native membrane vesicles from Torpedo marmorata electric organ by electron spin resonance (ESR) and fluorescence techniques. ESR spectra of spin-labelled cholestane (CSL) revealed that this steroid probe was incorporated into the AChR-rich membrane vesicles in regions which were to a certain exten...

A case is presented in which respiratory distress resulted from the production of methemoglobin Following application of topical benzocaine to a child’s oral mucous membrane. Modern local anesthetics are among the safest of administered agents, with few reported cases of morbidity or mortality. The use of topically applied local anesthetic agents is important in the atraumatic administration of...

PURPOSE This study compared pain, acceptance, and preference associated with 2 topical anesthetics: benzocaine gel and lidocaine patch (DentiPatch). METHODS Thirty patients aged 3 to 10 years participated in this within-subjects study. All children required identical or similar dental work bilaterally (restorations, extractions, endodontic procedures, or sealants). Subjects chose either Denti...

PURPOSE This study compared the efficacy of commonly used topical anesthetics using an objective measuring scale. METHODS The following were tested: 5% EMLA cream, 10% cocaine, 10% lidocaine, 10% benzocaine, 1% dyclonine, and a placebo. A special instrument was designed to serve the purpose of pressure application on the gingiva to obtain a threshold discomfort level in grams before and after...

The aim of our study is to identify the allergens in patients with leg ulcers who have contact dermatitis surrounding the skin of the ulcer and compare them with a control group consisting of patients with lower extremity contact dermatitis. A total of 40 patients with chronic leg ulcers (CLU) and contact dermatitis around the skin of ulcer were included in the study. As a control group, 20 pat...

INTRODUCTION Methemoglobinemia is a recognized complication of the use of topical anesthetic sprays. The true scope of the problem or the risk with different topical anesthetic sprays and endoscopic procedures is unknown. METHODS We retrospectively identified all cases of methemoglobinemia that occurred in a university affiliated community hospital from 2001 to 2007. RESULTS Eleven cases of...