OBJECTIVE To review the methodology of behavior genetics studies addressing research questions that go beyond simple heritability estimation and illustrate these using representative research on childhood and adolescent anxiety and depression. METHOD The classic twin design and its extensions may be used to examine age and gender differences in the genetic determinants of complex traits and d...

Comorbidity, defined as the manifestation of multiple disorders within an individual, has become the rule, rather than the exception. In youth, the co-occurrence of depression and anxiety is not only common, but leads to a more severe course of mental illness and poorer treatment response. Thus, researchers have aimed to understand the development of this frequent, and deleterious, relation. A ...

BACKGROUND The prevalence of diabetes is alarmingly high among Mexican American adults residing near the U.S.-Mexico border. Depression is also common among Mexican Americans with diabetes, and may have a negative influence on diabetes management. Thus, the purpose of the current study was to evaluate the associations of depression and anxiety with the behavioral management of diabetes and glyc...

There are many telling reasons to assemble a special issue of Depression and Anxiety at this time on venlafaxine, the dual serotonin-norepinephrine reuptake inhibitor, that is currently approved in the United States for the treatment of major depression and generalized anxiety disorder. First, there has been increasing evidence largely compiled by Bech and his colleagues in Denmark that antidep...

AIMS To identify correlates of impaired quality of life (QOL), anxiety, and depression in patients with an implantable cardioverter-defibrillator (ICD). METHODS AND RESULTS Surviving patients (n = 610) who received an ICD in our institution since 1989 completed the Short Form Health Survey (SF-36) and the Hospital Anxiety and Depression Scale. Mean age was 62.4 years with 18% females. In a mu...

BACKGROUND Prior research on the association between affective disorders and physical conditions has been carried out in developed countries, usually in clinical populations, on a limited range of mental disorders and physical conditions, and has seldom taken into account the comorbidity between depressive and anxiety disorders. METHODS Eighteen general population surveys were carried out amo...

Depression and anxiety can be severely detrimental to the health of both the affected woman and her offspring. In a rodent model of postpartum depression and anxiety, chronic social stress exposure during lactation induces deficits in maternal care and increases anxiety. Here, we extend previous findings by expanding the behavioral analyses, assessing lactation, and examining several neural sys...

objective: attention deficit hyperactivity disorder (adhd) is a chronic, highly prevalent neurodevelopmental disorder which affects 9% of school-age children. triple p-positive parenting program is an evidence-based parenting program reported to be useful in the management of this disorder. the aim of this randomized controlled trial was to evaluate the effectiveness of triple p in mothers of a...

The association between lifetime anxiety disorders, conduct disorder (CD), and antisocial personality disorder (ASPD) among adults in the community was explored. Data were drawn from the National Comorbidity Survey (n = 5,877), a representative community sample of adults aged 15-54 in the 48 contiguous US states. Multiple logistic regression analyses were used to determine the association betwe...