نتایج جستجو برای: becker muscular dystrophy

تعداد نتایج: 55949  

2017

© Springer Science+Business Media New York 2015 S. Grossbard, The Marriage Motive: A Price Theory of Marriage, DOI 10.1007/978-1-4614-1623-4_2 This chapter and the following are adapted from “A Theory of Allocation of Time in Markets for Labor and Marriage,” Economic Journal, Vol. 94, pp. 863–882, December 1984. While writing it I benefited from helpful comments from Gary Becker, Jerry Green (f...

2015
Zhe Wang Meral Reyhan Nancy Halnon Sarah N Khan Paul J Finn Pierangelo Renella Daniel B Ennis

Background Duchenne/Becker muscular dystrophy (D/BMD) is associated with early onset cardiomyopathy, with cardiac fibrosis amongst the earliest manifestations. Changes in conventional estimates of cardiac function (e.g. ejection fraction, EF) may occur late in Duchenne and Becker muscular dystrophy (DMD/BMD). Cardiac MRI tagging is a noninvasive imaging biomarker for quantifying ventricular dys...

2016
J. Martone F. Briganti I. Legnini M. Morlando E. Picillo O. Sthandier L. Politano I. Bozzoni

Substitutions, deletions and duplications in the dystrophin gene lead to either the severe Duchenne muscular dystrophy (DMD) or mild Becker muscular dystrophy depending on whether out-of-frame or in-frame transcripts are produced. We identified a DMD case (GSΔ44) where the correlation between genotype and phenotype is not respected, even if carrying a typical Duchenne mutation (exon 44 deletion...

Journal: :Journal of medical genetics 1997
A J van Essen A L Kneppers A H van der Hout H Scheffer I B Ginjaar L P ten Kate G J van Ommen C H Buys E Bakker

Detection of large rearrangements in the dystrophin gene in Duchenne and Becker muscular dystrophy is possible in about 65-70% of patients by Southern blotting or multiplex PCR. Subsequently, carrier detection is possible by assessing the intensity of relevant bands, but preferably by a non-quantitative test method. Detection of microlesions in Duchenne and Becker muscular dystrophy is currentl...

Journal: :Journal of medical genetics 2011
Byung Chan Lim Seungbok Lee Jong-Yeon Shin Jong-Il Kim Hee Hwang Ki Joong Kim Yong Seung Hwang Jeong-Sun Seo Jong Hee Chae

BACKGROUND Duchenne muscular dystrophy or Becker muscular dystrophy might be a suitable candidate disease for application of next-generation sequencing in the genetic diagnosis because the complex mutational spectrum and the large size of the dystrophin gene require two or more analytical methods and have a high cost. The authors tested whether large deletions/duplications or small mutations, s...

2017
Jeremy Edwards

This paper investigates the Becker-Woessmann (2009) argument that Protestants were more prosperous in nineteenth-century Prussia because they were more literate, a version of the Weber thesis, and shows that it cannot be sustained. The econometric analysis on which Becker and Woessman based their argument is fundamentally flawed, because their instrumental variable does not satisfy the exclusio...

Journal: :Physical review. E, Statistical, nonlinear, and soft matter physics 2010
Vitaly A Shneidman

Nucleation is considered for nonzero rate of change of the dimensionless barrier B, which is characterized by a finite, slowly varying "nonstationary index" N∝-(dB/dt). In the standard adiabatic approximation it is assumed that after the start of nucleation an N-independent nucleation flux is established instantaneously, with a quasi-steady-state (QSS) value determined by the current barrier B(...

Journal: :Cell transplantation 2013
Alok Sharma Hemangi Sane Prerna Badhe Nandini Gokulchandran Pooja Kulkarni Mamta Lohiya Hema Biju V C Jacob

Muscular dystrophy is a genetic disorder with no definite cure. A study was carried out on 150 patients diagnosed with muscular dystrophy. These included Duchenne muscular dystrophy, limb-girdle muscular dystrophy, and Becker muscular dystrophy variants. They were administered autologous bone marrow-derived mononuclear cells intrathecally and intramuscularly at the motor points of the antigravi...

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