Five patients are described who had repeated endoscopy because of continuing dyspeptic symptoms associated with a negative barium meal. They were found to have multiple recurring gastric erosions (aphthous ulcers). No common aetiological factor could be found, although four of these patients did have a mild or moderatley active superficial chronic gastritis. Conventional peptic ulcer therapy fa...

BACKGROUND Familial hiatal hernia has only rarely been documented. AIMS To describe the pattern of inheritance of familial hiatal hernia within an affected family. SUBJECTS Thirty eight members of a family pedigree across five generations. METHODS All family members were interviewed and investigated by barium meal for evidence of a hiatal hernia. RESULTS Twenty three of 38 family member...

Esophageal lipomas are benign tumors representing less than 0.5% of all gastrointestinal lipomas. They are typically detected incidentally but occasionally present with local symptoms and rarely with life-threatening complications. We describe a case of a 60-year-old man with progressive dysphagia and weight loss, who presented with several episodes of near asphyxiation secondary to regurgitati...

ménétrier's disease is a rare cause of hypertrophic gastropathy that is usually confined to the gastric body and fundus. it is characterized by giant rugae, hypoalbuminemia, and foveolar hyperplasia. here we report the case of a 26-year-old woman who presented with epigastric pain, postparandial nausea-vomiting, and weight loss. paraclinic evaluation revealed hypoalbuminemia and hypochromic mic...

The most common cause of gastric outlet obstruction in neonates and infants is hypertrophic pyloric stenosis. Pyloric web as a cause of gastric outlet obstruction is relatively rare in children and presents with non bilious vomiting, abdominal pain and failure to thrive. The onset of symptoms is usually late with nonspecific symptoms like vomiting and failure to thrive that seems to be due to n...

OBJECTIVES To assess the cost-effectiveness of alternative initial strategies in the management of uninvestigated dyspepsia in adult patients presenting to a primary care physician in Canada. METHODS Clinical decision-making was modeled based on outcomes data from the literature and expert opinion. Costs were obtained from official reimbursement lists, and a detailed microcosting analysis of ...

In 1794, Bayford described the post-mortem findings of a woman with lifelong dysphagia who eventually died of starvation, caused by oesophageal obstruction.' At post-mortem a right subclavian artery was identified passing aberrantly from a left-sided aortic arch behind the oesophagus, causing the woman's dysphagia. Dr Bayford referred to this extraordinary disposition ofthe right subclavian art...

n 83 year old woman presented with a two week history of right upper quadrant pain, pale stools, dark urine, and itch. In the previous five years there had been two episodes of similar symptoms, ultrasound scan showing multiple gall bladder calculi. Past history included hypertension, type 2 diabetes mellitus, and obesity. On examination she was not clinically icteric, apyrexic, but mildly tend...