............................................................................................................... 3 ACKNOWLEDGEMENT ............................................................................................. 4 INDEX OF FIGURES .................................................................................................. 7 1 BACKGROUND ...........................................

Cyclopentanone 1,2-monooxygenase, a flavoprotein produced by Pseudomonas sp. strain NCIMB 9872 upon induction by cyclopentanol or cyclopentanone (M. Griffin and P. W. Trudgill, Biochem. J. 129:595-603, 1972), has been utilized as a biocatalyst in Baeyer-Villiger oxidations. To further explore this biocatalytic potential and to discover new genes, we have cloned and sequenced a 16-kb chromosomal...

Valorization of lignin is essential for the economics of future lignocellulosic biorefineries. Lignin is converted into novel polymer building blocks through four steps: catalytic hydroprocessing of softwood to form 4-alkylguaiacols, their conversion into 4-alkylcyclohexanols, followed by dehydrogenation to form cyclohexanones, and Baeyer-Villiger oxidation to give caprolactones. The formation ...

Molecular dynamics simulations have been carried out to investigate the onset of surface condensation. On surfaces with different wettability, we snapshot different condensation modes (no-condensation, dropwise condensation and filmwise condensation) and quantitatively analyze their characteristics by temporal profiles of surface clusters. Two different types of formation of nanoscale droplets ...

introduction : the aim of this study was to examine and compare the apical sealing ability of ah26, ah plus and ah plus jet using a fluid filtration model. materials and methods : 70 single-rooted teeth were dissected from the cement-enamel junction. canals were prepared with protaper rotary system and manual k files and irrigated with 5.25% naocl and 17% edta. ten teeth were assigned as contro...

objective: the aim of this study is to measure the effect of different condensation pressure on the microleakage of mineral trioxide aggregate (mta).  methods: this study was an invitro study. a total of 55 single rooted straight-canal human extracted sound teeth free of cracks or calcification were selected. teeth were sectioned from cej region at 3 mm above the root apex. remaining specimens ...

Baeyer-Villiger monooxygenases (BVMOs) form a distinct class of flavoproteins that catalyze the insertion of an oxygen atom in a C-C bond using dioxygen and NAD(P)H. Using newly characterized BVMO sequences, we have uncovered a BVMO-identifying sequence motif: FXGXXXHXXXW(P/D). Studies with site-directed mutants of 4-hydroxyacetophenone monooxygenase from Pseudomonas fluorescens ACB suggest tha...