نتایج جستجو برای: bacterial barrier

تعداد نتایج: 291925  

Journal: :Journal of animal science 2011
P J A Wijtten J J Verstijnen T A T G van Kempen H B Perdok G Gort M W A Verstegen

Intestinal barrier function in pigs after weaning is almost exclusively determined in terminal experiments with Ussing chambers. Alternatively, the recovery in urine of orally administered lactulose can be used to assess intestinal permeability in living animals. This experiment was designed to study the barrier function of the small intestine of pigs over time after weaning. The aim was to rel...

Journal: :Gut 1999
G Schimpl M A Pabst G Feierl A Kuesz H Ozbey S Takahashi M E Höllwarth

BACKGROUND Bacterial translocation (BT) plays a major role in the pathophysiological process of spontaneous infections in portal hypertension (PH) and cholestatic jaundice. The major mechanisms promoting BT in experimental animal models are the disruption of the intestinal ecological equilibrium and disruption of the intestinal mucosal barrier. The enzymes xanthine dehydrogenase (XD) and xanthi...

2016
Shifu Wang Liang Peng Zhongtao Gai Lehai Zhang Ambrose Jong Hong Cao Sheng-He Huang

Bacterial meningitis remains the leading cause of disabilities worldwide. This life-threatening disease has a high mortality rate despite the availability of antibiotics and improved critical care. The interactions between bacterial surface components and host defense systems that initiate bacterial meningitis have been studied in molecular and cellular detail over the past several decades. Bac...

2017
Daniel Zhitnitsky Jessica Rose Oded Lewinson

For millennia, transition metals have been exploited to inhibit bacterial growth. We report here the potentiation of the anti-bacterial activity of transition metals by organic acids. Strong synergy between low, non-toxic concentrations of transition metals and organic acids was observed with up to ~1000-fold higher inhibitory effect on bacterial growth. We show that organic acids shuttle trans...

2017
Jun Zhou Bruce A Edgar Michael Boutros

Epithelial barrier function is maintained by coordination of cell proliferation and cell loss, whereas barrier dysfunction can lead to disease and organismal death. JNK signalling is a conserved stress signalling pathway activated by bacterial infection and tissue damage, often leading to apoptotic cell death and compensatory cell proliferation. Here we show that the stress inducible transcript...

Journal: :American journal of physiology. Gastrointestinal and liver physiology 2009
Junqiang Tian Li Hao Prakash Chandra Dean P Jones Ifor R Willams Andrew T Gewirtz Thomas R Ziegler

Short bowel syndrome (SBS) is associated with gut barrier dysfunction. We examined effects of dietary glutamine (GLN) or oral antibiotics (ABX) on indexes of gut barrier function in a rat model of SBS. Adult rats underwent a 60% distal small bowel + proximal colonic resection (RX) or bowel transection (TX; control). Rats were pair fed diets with or without l-GLN for 20 days after operation. Ora...

Journal: :Journal of neurology, neurosurgery, and psychiatry 2002
F Winkler S Kastenbauer U Koedel H W Pfister

Increased serum concentrations of tissue plasminogen activator correlate with an adverse clinical outcome in patients with bacterial meningitis Bacterial meningitis is the most common serious infection of the central nervous system. It is still characterised by high mortality and morbidity in adults. In this disease extensive perpetuated inflammation with leucocyte invasion into the central ner...

Journal: :jundishapur journal of microbiology 0
saba rehman department of microbiology and molecular genetics, quaid-e-azam campus, university of the punjab, lahore, pakistan; department of microbiology and molecular genetics, the women university multan, multan, pakistan shahbaz mujtaba ghauri department of ear, nose and throat, mayo hospital, king edward medical university, lahore, pakistan anjum nasim sabri department of microbiology and molecular genetics, quaid-e-azam campus, university of the punjab, lahore, pakistan; department of microbiology and molecular genetics, quaid-e-azam campus, university of the punjab, lahore-54590, pakistan. tel: +92-4235952833, fax: +92-4299230481

conclusions the bacterial isolates exhibited strong biofilm formation potential, while the extracts of acacia arabica significantly inhibited biofilm formation among the isolates and, therefore, could be executed in the development of cost-effective biofilm inhibitor medicines. results pseudomonas aeruginosa (kc417303-05), staphylococcus hemolyticus (kc417306), and staphylococcus hominis (kc417...

Journal: :Journal of biomedical materials research 1986
A H Hogt J Dankert J Feijen

Adhesion of coagulase-negative staphylococci (CNS) was studied onto a homologous series of methacrylate polymers and copolymers. The materials varied in wettability (contact angles) and were either positively or negatively charged (zeta-potential). Bacterial adhesion experiments performed in a parallel-plate perfusion system showed that positively charged TMAEMA-Cl copolymers significantly prom...

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