background wound healing is widely discussed in the medical literature. this study compared the healing effect of aloe vera extract and silver sulfadiazine in burn injuries in experimental rat model. methods sixteen rats were randomly assigned to one of two groups, each group 8 rats. a deep second-degree burn on the lower back and 3rd degree burn on upper back of each rat were created with a st...

background: chronic wounds are a serious problem for the patient and can increase the socioeconomic burden on the healthcare system and community. this study aimed at investigating the effect of angioplasty on chronic ischemic wound healing. methods: this study was conducted in sina hospital, affiliated to tehran university of medical sciences. thirty-eight patients with chronic ischemic wounds...

A fracture in bone results in a dramatic change of mechanical loading conditions at the site of injury. Usually, bone injuries heal normally but with increasing fracture gaps, healing is retarded, eventually leading to non-unions. The clinical situation of these two processes with different outcomes is well described. However, the exact relation between the mechanical environment and characteri...

background & aim: onosma stenosiphon has been used as herbal medicine for healing skin cuts and rashes. however, burn healing effect of this herb has not been yet reported in pharmaceutical texts. the aim of this study was to find out the effect of herb ointment on burn healing the superficial wounds post type ii burns of back and testis region in wistar rats. experimental: a total of 24 r...

BACKGROUND Critical limb ischemia due to peripheral arterial occlusive disease is associated with a severely increased morbidity and mortality. There is no effective pharmacological therapy available. Injection of autologous bone marrow-derived mononuclear cells (BM-MNC) is a promising therapeutic option in patients with critical limb ischemia, but double-blind, randomized trials are lacking. ...

BACKGROUND Bone and tendons exposure in diabetic patients requires flap reconstruction to avoid major limb amputation. However, for critical and unstable diabetic patients, revascularization and flap reconstruction may not be feasible. Skin grafts can be used in such a situation, and the purpose of this study is to evaluate this procedure in terms of treatment outcome. METHODS From October 20...