نتایج جستجو برای: b interferon

تعداد نتایج: 954732  

Journal: :Hawaii medical journal 1996
N Ching J Lumeng R Pang G Pang F W Or N Ching C Ching

The antiviral and immunomodulatory effects of interferon were assessed in the treatment of chronic hepatitis B in multi-ethnic patients to prevent viral replication and chronic liver damage. Five million units of recombinant interferon alpha-2b were administered three times a week for 48 weeks to a group of 18 chronic active hepatitis B patients. A complete response was defined as seroconversio...

Journal: :Proceedings of the National Academy of Sciences 1988

2005
Jennifer E Fenner Robyn Starr Ann L Cornish Jian-Guo Zhang Donald Metcalf Robert D Schreiber Kathleen Sheehan Douglas J Hilton Warren S Alexander Paul J Hertzog

Suppressor of cytokine signaling 1 (SOCS1) is a critical regulator of cytokine signaling and immune responses. SOCS1-deficient mice develop severe inflammatory disease, but are very resistant to viral infections. Using neutralizing antibody to type I interferon (IFN-a and IFN-b) and mice deficient in interferon-c or type I interferon receptor components (IFNAR1 or IFNAR2), we demonstrate here t...

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