نتایج جستجو برای: azelnidipine

تعداد نتایج: 144  

Journal: :Circulation journal : official journal of the Japanese Circulation Society 2010
Maki Hosoya Junko Ohashi Ayuko Sawada Aya Takaki Hiroaki Shimokawa

BACKGROUND The endothelium modulates vascular tone by synthesizing and releasing several vasodilating factors, including vasodilator prostaglandins, nitric oxide (NO) and endothelium-derived hyperpolarizing factor (EDHF). In the present study, we examined whether an angiotensin-receptor blocker, a calcium-channel blocker or their combination improved EDHF-mediated responses in diabetic apolipop...

Journal: :The Journal of surgical research 2011
Mansooreh Bagheri Behnam Moein Jahromi Hossein Mirkhani Zhabiz Solhjou Ali Noorafshan Ali Zamani Zahra Amirghofran

OBJECTIVE Impaired wound healing in diabetes is associated with decreased nitric oxide (NO) bioavailability in wound tissue. We hypothesized azelnidipine (AZL), a new calcium channel blocker with antioxidant properties, would enhance wound healing in streptozotocin-induced diabetic rats by restoring NO synthesis. METHODS Twelve male rats were taken as non-diabetic group. Twenty four rats were...

2010
Kazuomi Kario Masayuki Shirayama Katsutoshi Hiramatsu Kazuhito Shiosakai Mitsunori Sugiyama Kazuyuki Shimada

BACKGROUND Morning blood pressure (BP) surge, which exhibits an age-related increase, is a risk factor for stroke in elderly hypertensive patients, independently of the 24-h BP level. We studied the effect of the new baroreceptor sensitivity (BRS)-restoring Ca-channel blocker (CCB) azelnidipine (AZ) on this age-related morning BP increase. METHODS We conducted a 16-week prospective study to c...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید