نتایج جستجو برای: avoidance memory
تعداد نتایج: 294341 فیلتر نتایج به سال:
Background and Objective: Chlorogenic acid (CGA) is a major polyphenolic component of coffee. Reduction in the risk of a variety of diseases following CGA consumption has been mentioned in recent studies. The effect of CGA on learning and memory in rats with cognitive deficit induced by intracerebroventricular streptozotocin (STZ) and acetylchoinesterase (AChE) activity was evaluated in this s...
Background: It has been known that Brain-Derived Neurotrophic Factor (BDNF) is involved in neural survival and long term memory (LTM). Here we hypothesized that BDNF as a potent neurotrophic factor might modulate amnestic effect induced by morphine. Objectives: The aim of this study was to examine whether infusion of exogenous BDNF in the CA1 regions of the dorsal hippocampi could ameliorate me...
Medicinal plants have attracted global attention due to their high levels of antioxidant components for prohibiting or improving various diseases including brain and memory disorders. This study was designed to investigate if the antioxidant effect of Sidr (Zizyphusspina-christi) extract can help to improve the scopolamine induced impairment of memory in Wistar rats. Animals were randomly...
ارزیابی یادگیری و حافظه موش صحرایی صرعیشده توسط تزریق داخلهیپوکمپی اسید کاینیک پس از دریافت بربرین
Background and Objective: Epilepsy is the second most common disease of the central nervous system. Since memory disturbance is rather commin in epileptic patients, 20, the goal of this study was to assess the effect of berberine on memory deficit in epileptic rats. Materials and Methods: In this study, 32 male rats weighing 190-240 g were divided into 4 groups: sham, sham receiving berberi...
Background and Objective: It has been shown that cannabinoids exert widespread effects on cognitive functions. An overlapping distribution of GABA with cannabinoid receptors has been reported in some brain structures such as dorsal hippocampus. Thus, the functional interactions between cannabinoid and GABAergic systems in cognitive control seem possible. The present study evaluated the potentia...
Introduction: Evidence indicates that morphine impairs memory process. Ghrelin hormone has been linked to learning and memory processes and modulates reward properties of addictive drugs. In this study we examined the role of middle septal ghrelin receptors in the effects of morphine on memory consolidation in passive avoidance learning. Materials & Methods: In this experimental study, 91 ma...
Background & Aims: Previous research has shown that adult male rats’ castration reduces memory and learning. On the other hand, zinc chloride has a positive impact on memory and learning in some studies. Therefore, the aim of this study was to investigate effects of zinc chloride on passive avoidance memory of male rats, in gonadectomized peri-pubertaly. Materials & Methods: In this expe...
Intracerebroventricular (ICV) injection of streptozotocin (STZ) in rats is followed by long-term and progressive deficits in learning, memory, and cognitive performance which is somewhat similar to sporadic Alzheimer’s disease (SAD). Epidemiological studies suggest that non-steroidal anti-inflammatory drugs (NSAIDs) could delay or slow the clinical expression of SAD. Therefore, the benefi...
Introduction: Lead (Pb) is a neurotoxin that its different effects on the central nervous system are well-known. Previous studies have reported the potent effects of vitamin C on memory.The present study was undertaken to evaluate the protective effects of vitamin C against leadinduced amnesia. Methods: Male Wistar rats were divided into 4 groups: the control (saline), negative contr...
introduction: the role of serotonergic fibers in avoidance learning is controversial. involvement of the dorsal raphe nucleus (drn), the main source of hippocampal projecting serotonergic fibers in acquisition, consolidation and retrieval of passive avoidance (pa) learning, was investigated by functional suppression of this area. materials and methods: drn functional inactivation was done by li...
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