Pathological response of breast cancer to neoadjuvant chemotherapy (NAC) presents great variability, and new prognostic biomarkers are needed. Our aim was to evaluate the association of the epidermal growth factor receptor gene (EGFR) polymorphism R497K (rs2227983) with prognostic features and clinical outcomes of breast cancer, including the pathological response to NAC and the recurrence-free...

Background: The direct agglutination test (DAT) has proved to be a very important serodiagnostic tool combining high levels of intrinsic validity and ease of performance. Otherwise, fast agglutination screening test (FAST) utilises only one serum dilution making the test very suitable for the screening of large populations. Results: We have tested FAST and DAT for the detection anti-Leishmania ...

Recent developments in technologies such as Automatic Vehicle Location (AVL) and advanced control systems have stimulated new interest in bus priority facilities using traffic signals. The use of AVL systems has generated opportunities for implementing flexible busspecific priority strategies according to performance. The extent of the opportunities available depends very much on the architectu...

Lutzomyia longipalpis is the main vector of Leishmania infantum chagasi, the causative agent of American visceral leishmaniasis (AVL). Although there is strong evidence that Lu. longipalpis is a species complex, not all data concerning populations from Brazil support this hypothesis. The issue is still somewhat controversial for this large part of Lu. longipalpis distribution range even though ...

Methanol as a biofuel is an environmentally friendly substitute for pure diesel and can be obtained from biomasses. The use of biofuels such as methanol for the combustion process is associated with positive impacts on the environment. Using pure methanol or a blend of diesel/methanol fuel in motorized vehicles has been proposed by researchers. In this paper, pure methanol was injected into the...

In this study, the effects of adding ethanol and diethyl ether to diesel fuel on combustion characteristics NO emissions were numerically investigated. 100% (D100) by volume 90% diesel+10% blend (D90E10), 80% diesel+20% (D80E20), ethanol+10% (D80E10DEE10) 85% diesel+ 10% ethanol+5% mixture (D85E10DEE5) was used as fuel. Analyzes carried out using a single cylinder direct injection engine at 200...

The burner-type regeneration diesel particulate filter is one of the most widely used filters. Using AVL FIRE, a 3D model (DPF) was established, and simulation analyses were carried out. effects exhaust parameters (temperature, mass flow rate, soot load) structural (channel density, inlet/outlet channel ratio, length–diameter ratio) on distribution (soot concentration thickness) analyzed. resul...