In this review, we focus on the role of the Shank family of proteins in autism. In recent years, autism research has been flourishing. With genetic, molecular, imaging and electrophysiological studies being supported by behavioural studies using animal models, there is real hope that we may soon understand the fundamental pathology of autism. There is also genuine potential to develop a molecul...

Autism spectrum disorder is characterized by patterns of delay and deviance in the development of social, communicative, and cognitive skills that arise in the first years of life. Although frequently associated with intellectual disability, this condition is distinctive in its course, impact, and treatment. Autism spectrum disorder has a wide range of syndrome expression and its management pre...

autism is a developmental disability with age of onset in childhood (under 3 years old), which is characterized by definite impairments in social interactions, abnormalities in speech, and stereotyped pattern of behaviors. due to the progress of autism in recent decades, a wide range of studies have been done to identify the etiological factors of autism. it has been found that genetic and envi...

Due to the myriad of problems associated with autism, parents often consider alternative treatments. The investigation was undertaken to determine the effects of the Tomatis Method on language skills in children with autism utilizing a randomized, double-blind, placebo-controlled, crossover design. The results indicated that although the majority of the children demonstrated general improvement...

This editorial discusses the importance of autism research, noting areas of progress and ongoing challenges and focusing on studies of the etiology, pathophysiology, and treatment of autism spectrum disorders.

Despite our ability to reliably diagnose autism spectrum disorder (ASD) from 18-24 months of age, and the widespread use ASD screening tools, median age diagnosis has hovered around 4 years age. In this volume The Journal, Pierce et al describe an exciting new model for detecting initiating earlier treatment ASD—which may lead improved developmental outcomes. Get SET Early examines entire proce...

Background: Despite many efforts, the etiology of autism remains unknown. Food allergy has been suggested as a pathogenic factor in Autism Spectrum Disorder (ASD). Our aim in this study was to determine whether food allergy could be considered as a risk factor for autistic children. Methods: Thirty-nine autistic children were examined by the skin prick test (SPT), and total serum IgE was eva...