A facile and green route was introduced to synthesize Au nanoparticles immobilized on halloysite nanotubes (AuNPs/HNTs) used for surface-enhanced Raman scattering substrates. The naturally occurring HNTs were firstly functionalized with a large amount of -NH(2) groups by N-(β-aminoethyl)-γ-aminopropyl trimethoxysilane (AEAPTES), which possesses one lone electron pair and will "anchor" Au ions t...

To improve glioma targeting delivery efficiency and to monitor drug delivery and treatment outcome, a novel tumor microenvironment sensitive size-shrinkable theranostic system was constructed and evaluated. The G-AuNPs-DC-RRGD system was constructed by fabricating small sized gold nanoparticles (AuNPs) onto matrix metalloproteinase-2 (MMP-2) degradable gelatin nanoparticles (GNPs), doxorubicin ...

This study reports the biological synthesis of gold nanoparticles (AuNPs) by the reduction of HAuCl4 by using of Eclipta prostrata leaf extract as the reducing and stabilizing agent. AuNPs were characterized using Ultraviolet–visible (UV-vis) spectroscopy, X-ray diffraction (XRD), Fourier Transform-Infrared (FTIR) spectroscopy, Scanning Electron Microscopy (SEM), High Resolution-Transmission El...

This paper presents the fabrication of a molecularly imprinted, polymer-based disposable electrochemical sensor for paraoxon (PO) determination. The sensor was based on a screen-printed carbon electrode (SPCE) modified with a surface molecularly imprinted poly (p-aminothiophenol) (PATP)/gold nanoparticles (AuNPs) composite film, which consisted of a PATP outer layer and an AuNPs inner layer. We...

The development of a green and facile strategy for synthesizing high stable gold nanoparticles (AuNPs) is still highly challenging. Additionally, the main problems regarding AuNPs based colorimetric sensors are their poor selectivity and low sensitivity, as well their tendency to aggregate during their synthesis and sensing process. Herein, we present an in-situ reduction strategy to synthesize...

Here, we studied the effect of the size, shape, and surface charge of Au nanoparticles (AuNPs) on amyloid beta (Aβ) aggregation on a total brain lipid-based supported lipid bilayer (brain SLB), a fluid platform that facilitates Aβ-AuNP aggregation process. We found that larger AuNPs induce large and amorphous aggregates on the brain SLB, whereas smaller AuNPs induce protofibrillar Aβ structures...

Magnetite decorated with gold nanoparticles (Fe3O4-AuNPs) is a ferrimagnetic material with unprecedented applications in immunosensors, as a contrast agent for imaging diagnosis, and for the photothermal ablation of tumor cells. Here, we show the preparation of controlled amounts of Fe3O4-AuNPs without organic solvents, surfactants, or heat treatment. For this, we have developed a customized na...

In our efforts to develop new approaches to treat and prevent human vascular diseases, we report herein our results on the proliferation and migration of human smooth muscles cells (SMCs) and endothelial cells (ECs) using epigallocatechin-3-gallate conjugated gold nanoparticles (EGCg-AuNPs) as possible alternatives to drug coated stents. Detailed in vitro stability studies of EGCg-AuNPs in vari...

In this research, graphene nanosheets were functionalized with cationic poly (diallyldimethylammonium chloride) (PDDA) and citrate-capped gold nanoparticles (AuNPs) for surface-enhanced Raman scattering (SERS) bio-detection application. AuNPs were synthesized by the traditional citrate thermal reduction method and then adsorbed onto graphene-PDDA nanohybrid sheets with electrostatic interaction...

The nucleation potential and deposition time was used to control the size and the amount of the deposited AuNPs, respectively, for obtaining an optimum coverage of AuNPs on the electrode surface. The effect of deposition potential on particle size and density for a constant charge passed (6 × 10−4 C) has been investigated. It is clear from the images (see Figure S1) that the size of the AuNPs d...