Augmentation index (AIx) is derived from pressures imposed on the left ventricle as a result of systolic peripheral wave reflection. Differences in AIx response to an acute stress, such exercise, may prove useful for predicting future cardiovascular risk younger adults, but less known about whether this differs between men and women. PURPOSE: To examine there are sex differences bout exercise h...

BACKGROUND AND PURPOSE We sought to establish the relation between the pulsatile components of pressure and flow waveforms in the carotid artery and their change with age. METHODS Distention (pressure) and axial flow velocity waveforms were recorded noninvasively and simultaneously from the common carotid artery of 56 healthy subjects aged 20 to 72 years. RESULTS There was a close relation ...

OBJECTIVES/HYPOTHESIS To compare voice outcomes after vocal fold augmentation using a trial (temporary) vocal fold injection (VFI) versus long-term augmentation in patients diagnosed with vocal fold atrophy. STUDY DESIGN Retrospective, single-blinded study. METHODS Nineteen patients diagnosed with vocal fold atrophy underwent trial VFI and subsequent long-term augmentation. Voice Handicap I...

Multinomial models with unknown index (“sample size”) arise in many practical settings. In practice, Bayesian analysis of such models has proved difficult because the dimension of the parameter space is not fixed, being in some cases a function of the unknown index. We describe a data augmentation approach to the analysis of this class of models that provides for a generic and efficient Bayesia...

Increased large artery stiffness occurs in a range of inflammatory conditions indicating an ageing of the vasculature and additionally being an independent risk factor for cardiovascular events. We determined large artery parameters in adults with cystic fibrosis (CF). 50 clinically stable adult patients with CF (mean+/-sd age 28.0+/-8.2 yrs) and 26 controls matched for age, sex and body mass i...

The augmentation index (AIx) and "oscillatory" compliance (C(2)) are wave contour analysis parameters for the central aorta (P(ao)) and radial artery pressure wave (P(rad)), respectively. Both are sensitive to cardiovascular risk factors such as aging, hypertension, and diabetes and have been proposed as prognostic markers for cardiovascular disease. In this work, we studied the relation betwee...