OBJECTIVE Increased prevalence of celiac disease (CD) and autoimmune thyroid disorders (ATD) in patients with Type 1 diabetes mellitus (T1D) has been widely reported. Such an association may lead to adverse effects on the growth, bone metabolism and fertility, and response to therapy may become difficult. The aim of this study was to evaluate the clinical findings and HLA typing results in pati...

OBJECTIVE Implicit memory, defined as the recollection of knowledge unconsciously, automatically, and without being aware of it, is different than explicit memory, in which knowledge is recollected consciously, while being aware of it. In the present study, the implicit memory performance of patients with mild cognitive impairment (MCI) and Alzheimer's type dementia (ATD) (different stages) wer...

The firing behavior of seven antidromically identified ascending tract of Deiters (ATD) neurons was recorded in one alert squirrel monkey trained to pursue moving targets and to fixate visual targets at different distances from the head during whole body rotation. 2. ATD cells generated signals related to contralateral horizontal smooth pursuit eye movements and to ipsilateral angular and linea...

Alcohol is well documented to affect male fertility. The association between alcohol use disorders and tuberculosis has long been known and well described. Taking into account that both alcohol and anti-tuberculosis drugs (ATD) could have negative impacts on male gonads, an increase in adverse effects is probable. The study aimed to determine combine effects of long-term alcohol consumption and...

Glutamate receptor ion channels (iGluRs) are excitatory neurotransmitter receptors with a unique molecular architecture in which the extracellular domains assemble as a dimer of dimers. The structure of individual dimer assemblies has been established previously for both the isolated ligand-binding domain (LBD) and more recently for the larger amino terminal domain (ATD). How these dimers pack ...

Previous research has shown that low central serotonin, induced by acute tryptophan depletion (ATD), results in depressed mood and impairs cognition in healthy volunteers with a predisposition for depression. It remains unknown whether ATD affects emotional processing via mood changes or directly. In the present study we investigated the interaction between vulnerability for depression and the ...

To elucidate serotonin modulation of selective attention, 13 volunteers (21-30 years) were studied in two sessions, 5 h after either acute tryptophan depletion (ATD) that decreases brain serotonin synthesis, or control-mixture ingestion (randomized, double-blind, cross-over design). Simultaneous electroencephalogram and magnetoencephalogram were measured during dichotic listening of two concurr...

AIM To show characteristic ocular surface findings caused by conjunctivochalasis (CCh) in dry eye patients with or without aqueous tear deficiency (ATD). DESIGN Comparative non-interventional cases. PATIENTS AND METHODS Clinical data of five ATD patients without CCh (group A), eight CCh patients with ATD (group B), and eight CCh patients without ATD (group C) were retrospectively reviewed. ...

Involuntary attention shifting, i.e., detecting and orienting to unexpected stimulus changes, may be altered at low brain serotonin (5-hydroxytryptamine; 5-HT) levels. This was studied in 13 healthy subjects (21-30 years old; 6 females) by using a dietary challenge, acute tryptophan depletion (ATD), which decreases 5-HT synthesis in the brain. Five hours after ingestion of either ATD or control...

One method of understanding the general mechanical response of a complex system such as a vehicle, a human surrogate, a bridge, a boat, a plane, etc., is to subject it to an input, such as an impact, and obtain the response time-histories. The responses can be accelerations, velocities, strains etc. In general, when experiments of this type are run the responses are contaminated by sample-to-sa...