In various polarized cells, positions of nuclei are often off-center. However, extrinsic signals regulating nuclear off-centering and its biologic roles remain to be elucidated. In Caenorhabditis elegans, polarity of the EMS cell undergoing asymmetric division is regulated by the MOM-2/Wnt and MES-1 signals from its posterior neighbor P2 cell. We show that after divisions of different cells inc...

A new study shows that SPEECHLESS determines cell fate in the stomatal lineage but is inherited equally by daughter cells following an asymmetric cell division. The polarity determinant BASL acts as a MAPK scaffold, targeting SPEECHLESS for degradation in the larger daughter cell.

We read with interest the article by Maron et al.1 We would like to commend them for utilizing the term, “hypertrophic cardiomyopathy,” in this report, instead of the term, “asymmetric septal hypertrophy,” which has now proven rather nonspecific. We were also pleased to note that Maron et al1 now recognize that asymmetric septal hypertrophy is not pathognomonic of hypertrophic cardiomyopathy. N...

Microproblematica are microfossils whose suprageneric taxonomic status is unknown. Many microproblematica display an encrusting way of life and can therefore be included in the group of “micro-encrusters” that during the Upper Jurassic were conspicuous components of microbial carbonate crusts (e.g. LEINFELDER et al., 1993; SCHMID, 1996; DUPRAZ & STRASSER, 1999, 2002). These forms are widespread...

We compute that the growth of the origin occupation-time variance up to time t in dimension d = 2 with respect to asymmetric simple exclusion in equilibrium with density ρ = 1/2 is in a certain sense at least t log(log t) for general rates, and at least t(log t)1/2 for rates which are asymmetric only in the direction of one of the axes. These estimates are consistent with an important conjectur...

Hydrogenolysis is an important synthetic method in organic chemistry, and has been widely applied in industrial processes, natural product synthesis, and the removal of waste materials. In practice, most hydrogenolysis reactions have been used for the synthesis of racemic or achiral compounds. Very few studies on asymmetric homogeneous hydrogenolysis have been reported. The first example, repor...

the improved estimator of the variance in the general linear model is presented under an asymmetric linex loss function.

The question what specific functions the production of emotional tears fulfills has received only limited attention of behavioral scientists. We report the results of two studies on the social impact of emotional tears. In Study 1 (96 Dutch females), perceived helplessness and felt connectedness predicted the willingness to help a person depicted as crying tearfully, while perceived friendlines...

Although little is known about how asymmetric cell division in plants is regulated, recent discoveries provide a starting point for exploring the mechanisms underlying this process. These studies reveal parallels with asymmetric division in yeast and animals, but also point to regulated cell expansion as a new mechanism of asymmetric division in plants.