OBJECTIVES The aim of this study was to investigate the safety and the efficacy of Korean herbal, western and combination medicine use in patients with abnormal liver function tests. METHODS We investigated nerve disease patients with abnormal liver function tests who were treated with Korean herbal, western and combination medicine at Dong-Eui University Oriental Hospital from January 2011 t...

BACKGROUND Autoimmune hepatitis (AIH) is a relapsing inflammatory disease of the liver of unknown cause. Little is known about AIH in Saudi Arabia. OBJECTIVES Our aim is to 1) identify the special clinical or histological features in our patients, 2) describe the initial response to immunosuppressive therapy and long term relapse, 3) identify clinical and laboratory predictors of response to ...

Cardiovascular and other blood related diseases are fast replacing communicable diseases; therefore there is need to constantly monitor our specific deleterious parameters and their associates. In this work, blood samples were collected to determine biochemical parameters: total cholesterol (TC), high density lipoproteincholesterol (HDL C), low density lipoproteincholesterol (LDL-C), very low d...

A nonsynonymous E167K (rs58542926 C/T) variant in TM6SF2 gene was recently associated with nonalcoholic fatty liver disease (NAFLD). We explored the association between E167K and plasma concentrations of alanine (ALT) and aspartate (AST) aminotransferases through a meta-analysis. We also estimated the strength of the effect across diverse liver phenotypes, including NAFLD and chronic viral hepa...

BACKGROUND A detrimental interaction between smoking and alcohol consumption with respect serum γ-glutamyltransferase (γ-GT) has recently been described. The underlying mechanisms remain unknown. The present work aimed to provide further insights by examining similar interactions pertaining to aspartate and alanine transaminase (AST, ALT), routine liver markers less prone to enzyme induction. ...

OBJECTIVE To compare various biochemical markers i.e. APRI (AST to platelet ratio index), aspartate aminotransferase (AST) alanine aminotransferase (ALT) ratio, FIB-4 (AST, platelet, AST and age) with biopsy for assessing the severity of hepatic fibrosis in patients with hepatitis C. STUDY DESIGN Descriptive study. PLACE AND DURATION OF STUDY Medical Department, Liaquat University of Medica...

Diabetes mellitus (DM) is a group of metabolic diseases resulting from impaired insulin secretion and/or action. DM is characterized by hyperglycemia that can lead to the dysfunction or damage of organs, including the salivary glands.The aim of this study was to compare the levels of salivary lactate dehydrogenase (LDH), aspartate aminotransferase (AST), and alanine aminotransferase (ALT) in di...

UNLABELLED Triathlon competition is dependent on the athletes' ability to perform each discipline at optimal time, without excessive fatigue influencing the next one. OBJECTIVES Determine the effects of a long distance triathlon on biochemistry parameters related to liver function. DESIGN AND METHODS Blood samples from six athletes were collected before (T = 0) and immediately after the tri...