Introduction Among women ages 15–44, 6.7 million have impaired ability to have children, 1.5 million are infertile, and 7.4 million have used infertility services in their lifetime (www.cdc.gov/nchs/fastats/fertile.htm). Now more than ever, women are having their fertility manipulated by reproductive endocrinology clinics and are undergoing multiple cycles without knowing the long-term effects ...

The use of assisted reproductive technology is increasing rapidly. Research, although sparse, has resulted in inconsistent findings as to the developmental prognosis for infants conceived by assisted reproductive techniques such as in vitro fertilization and the use of fertility drugs. In the present study, the authors compared twins who were spontaneously conceived with those who were conceive...

For many years, the management of male-factor infertility has been empirical rather than evidence-based. In current clinical practice, assisted reproductive techniques are the most successful methods of alleviating male-factor infertility. To date, it remains unclear what adjuvant actions can be taken to improve the outcome of assisted reproductive techniques for male-factor infertility. Eviden...

Heterotopic pregnancy (HP) is the simultaneous occurrence of intra- and extrauterine pregnancies. It is a rare event in spontaneous pregnancies with an incidence of less than 1:15000 however the frequency has increased to 1% in accordance with the widespread use of assisted reproductive techniques (ART). The pre-operative diagnosis of this condition is generally difficult and it would be life t...

This Application Note demonstrates the capability of the Agilent 1290 Infi nity 2D-LC Solution for heart-cutting applications. As an example, a minor impurity is resolved by heart cutting from a co-eluting main compound. The minor impurity, which is isolated on a second-dimension column after heart cutting, is verifi ed by additional spiking and statistical evaluation of the separation performa...

BACKGROUND It is estimated that there is at least a 2-fold rise in the incidence of monozygotic twinning after assisted reproductive technology compared with natural conception. This can result in adverse pregnancy outcomes. METHODS We searched MEDLINE, EMBASE and SCISEARCH for studies that estimated the risk of monozygotic twinning and its association with any particular assisted reproductiv...

The information and views set out in this publication are those of the author(s) and do not necessarily reflect the official opinion of the Commission. The Commission does not guarantee the accuracy of the data included in this study. Neither the Commission nor any person acting on the Commission's behalf may be held responsible for the use which may be made of the information contained therein.