Laboratory liver tests are broadly defined as tests useful in the evaluation and treatment of patients with hepatic dysfunction. The liver carries out metabolism of carbohydrate, protein and fats. Some of the enzymes and the end products of the metabolic pathway which are very sensitive for the abnormality occurred may be considered as biochemical marker of liver dysfunction. Some of the bioche...

Treatment of rats with cefazolin in vivo significantly suppressed activity of alanine and aspartate aminotransferases in serum and in the liver, brain, kidney, and heart. Simultaneous administration of pyridoxal further reduced enzyme activity except in the liver, where there was no change. Pyridoxal 5'-phosphate partly reversed the decreased enzyme activity in the serum, liver, and kidney, but...

The aim of this study was to investigate the effect of chlorfenvinphos administered at a single dose of 0.02 LD50 on the activity of serum of liver damage indicatory enzymes, such as β-glucoronidase (BGR), acid phosphatase (AcP) and alanine and aspartate aminotransferases (ALT and AST), as well as on the activities of superoxide dismutase (SOD) and catalase (CAT) in erythrocytes and liver. The ...

∗ Corresponding author V-1 Immunitor (V1) is an oral AIDS vaccine currently being used as a therapeutic modality by HIV-positive patients. Upon interim analysis of phase I safety trial it has been discovered that patients who had elevated liver enzymes aspartate (AST/SGOT) and alanine (ALT/SGPT) aminotransferases have experienced the reduction of enzyme levels back to normal. Two other hepatiti...

Results of traditional laboratory tests of liver function were correlated with the clinical course in 26 pediatric patients after liver transplantation. On the basis of clinical outcome after transplantation, the patients were divided into two groups: (a) uncomplicated course with short hospital stay, and (b) post-transplantation course complicated by multiple clinical problems. The patterns of...

Amino acid level is well known indicator of plant resistance to aphids. Our earlier studies showed that grain aphid (Sitobion avenae F.) infestation caused changes in the activity of the enzymes connected with amino acid biosynthesis and the transformation to defensive secondary metabolites within triticale tissues. However, there are not data on the significance of aminotransferases in these p...

In each of 10 highly hyperglycemic decompensated diabetics with ketoacidosis, we found a markedly increased serum activity of two lysosomal hydrolases (N-acetyl--glucosaminidase and -glucuronidase). This was also true to a lesser degree of five diabetics with less severe decompensation and without ketoacidosis. The activity of both enzymes and the degree of hyperglycemia were highly correlated....

OBJECTIVE To evaluate the frequency of non-alcoholic fatty liver disease (NAFLD) in patients with type 2 diabetes mellitus (DM2) and to describe its risk factors. SUBJECTS AND METHODS Blood samples of 78 patients were collected for assessment of glycemic and lipid profile, liver enzymes, TNF-alpha and HOMA-IR. The diagnosis of NAFLD was established by ultrasound. RESULTS NAFLD was observed ...

Currently no reports are available from Egypt regarding occupational exposure to nickel and its effects on the liver. The aim of this study was to assess the liver function of workers occupationally exposed to nickel. Standard liver function tests were applied to blood samples from 25 nickel-plating workers in Damietta, Egypt and 30 administrative workers as a reference group. Levels of urine n...

OBJECTIVES To determine the prevalence of insulin resistance (IR) in non-diabetic patients with chronic hepatitis C, and to assess the association between IR, laboratory parameters and histological findings. SUBJECTS AND METHODS Eighty-two patients had their serum analyzed for glucose, lipid profile, C-reactive protein (CRP), ferritin, alanine aminotransferase (ALT), aspartate aminotransferas...