Aspartame is a phenylalanine containing sweetener, added to foods and drinks, which avoided in phenylketonuria (PKU). However, the amount of provided by aspartame unidentifiable from food drinks labels. We performed cross-sectional online survey aiming examine accidental consumption PKU. 206 questionnaires (58% female) were completed. 55% respondents (n = 114) adults with PKU or their parent/ca...

Aspartame and Sodium cyclamate are two synthetic sweeteners used extensively in developing world. The study aims to assess the comparative effect of these on lipid profiles, biochemical parameters liver kidney function histological changes. Twenty male albino rats were separated into 5 groups 4 each. Group 1 fed normal diet water, whereas those Groups 2, 3, 4, received 50 mg/kg sodium cyclamate...

Diabetic kidney disease (DKD) has become a global health concern, with about 40% of people living type 1 and 2 diabetes mellitus developing DKD. Upregulation vascular endothelial growth factor (VEGF) in the is significant pathology DKD associated increased glomerular permeability. To date, however, current anti-VEGF therapies have demonstrated limited success treating Recent studies shown that ...

In order to better assess non-nutritive sweetener (NNS) consumption, measurement tools with greater utility are needed. The objective of this investigation is to determine the reproducibility and validity of a newly developed NNS food frequency questionnaire (NNS-FFQ) that measures five types of NNS (saccharin, aspartame, acesulfame potassium, sucralose and erythritol). Adult participants (n = ...