Abstract There are discrepancies in the literature regarding course of central auditory processes (CAP) maturation typically developing children and adolescents. The purpose study was to provide an overview age – related improvement CAP Polish primary secondary school students aged 7–16 years. 180 children/adolescents, subdivided into 9 categories, 20 adults (aged 18–24 years) performed Dichoti...

DAF-16 target genes are employed as reporters of the insulin/IGF-1 like signal pathway (IIS), and this is notably true when Caenorhabditis elegans (C. elegans) is used to study the action of anti-aging compounds on IIS activity. However, some of these genes may not be specific to DAF-16, even if their expression levels are altered when DAF-16 is activated. Celecoxib was reported to extend the l...

T he International Workshop on ContentBased Multimedia Indexing (CBMI) aims to annually bring together the various communities involved in all aspects of content-based multimedia indexing—from retrieval and browsing to visualization and analytics. The 14th edition of CBMI (http://cbmi2016.upb.ro) achieved its goal, maintaining the tradition of the previous successful events, the first of which ...

A refined model of the colchicine site on tubulin was used to design an improved analog of the pyrrole parent compound, JG-03-14. The optimized compound, NT-7-16, was evaluated in biological assays that confirm that it has potent activities as a new colchicine site microtubule depolymerizer. NT-7-16 exhibits antiproliferative and cytotoxic activities against multiple cancer cell lines, with IC(...