The purposes of the present study were to determine the effectiveness of infiltration anesthesia in the mandibular primary molars, and how patient age, tooth location, and anesthetic type relate to the quality of anesthesia. Data were derived from 66 subjects, 42-72 months old, requiring restorative treatment in mandibular primary molars. Infiltration anesthesia was provided with mepivacaine hy...

Introduction: Local anesthetics have been in use in dental practice for more than 100 years. The advent of local anesthetics with the development of nerve blockade injection techniques heralded a new era of patient comfort while permitting more extensive and invasive dental procedures. Discussion: Today’s availability of a variety of local anesthetic agents enables dentists to select an anesthe...

Part 1 comments on the types of local anaesthetics (LAs); it provides a better understanding of the mechanisms of action of LAs, and their pharmacokinetics and toxicity. It reviews the newer LAs such as levobupivacaine, ropivacaine, and articaine, and examines the newer structurally different LAs. The addition of adjuvants such as adrenaline, bicarbonate, clonidine, and corticosteroids is explo...