Ventilation and arterial oxygen saturation have been measured in 18 patients during anaesthesia with ether or halothane carried in air. All patients were ventilated artificially with a Jefferson ventilator at a frequency of 16 breaths per minute and variable tidal volume. Ventilation has been expressed as a percentage of Radford's standard, Nunn's standard and the patient's pre-operative restin...

Ventilation and arterial oxygen saturation have been measured in 18 patients during anaesthesia with ether or halothane carried in air. All patients were ventilated artificially with a Jefferson ventilator at a frequency of 16 breaths per minute and variable tidal volume. Ventilation has been expressed as a percentage of Radford's standard, Nunn's standard and the patient's pre-operative restin...

BACKGROUND The oxygen saturation of haemoglobin is reduced in high altitude-living organisms. Increase in the hematocrit is responsible for rise in the hemoglobin concentration so that the oxygen carrying capacity in the hypobaric hypoxic subject is elevated. OBJECTIVES To compare two different high altitude populations, in order to study the relationship between arterial oxygen saturation an...

BACKGROUND Pulse oximeters continuously monitor arterial oxygen saturation. Continuous monitoring of venous oxygen saturation (SvO2) would enable real-time assessment of tissue oxygen extraction (O2E) and perfusion changes leading to improved diagnosis of clinical conditions, such as sepsis. METHODS This study presents the proof of concept of a novel pulse oximeter method that utilises the co...

The pulmonary vascular response to alveolar hypoxia with and without halothane exposure was measured in dogs. Hypoxia increased pulmonary artery pressure (Ppa) and pulmonary vascular resistance (PVR) so that in each case inverse linear relationships were found with arterial oxygen saturation. These responses were highly significant and reproduceable but varied greatly between individuals. Halot...

BACKGROUND Liver transplant is the only definitive treatment for many patients with end stage liver disease. Presence and severity of preoperative pulmonary disease directly affect the rate of postoperative complications of the liver transplantation. Arterial blood gas (ABG) measurement, performed in many transplant centers, is considered as a traditional method to diagnose hypoxemia. Because A...

INTRODUCTION This study investigates the relation between changes in pulse oximeter oxygen saturation (SpO2) and changes in arterial oxygen saturation (SaO2) in the critically ill, and the effects of acidosis and anaemia on precision of using pulse oximetry to predict SaO2. PATIENTS AND METHODS Forty-one consecutive patients were recruited from a nine-bed general intensive care unit into a 2-...