myocardial infarction is a common presentation of coronary artery disease and the leading cause of death worldwide. the present study was investigated potential resistance to ischemia-reperfusion (i/r) injuries following administration of methanolic (meoh) extract of scrophularia frigida (s. frigida) in isolated rat heart. male wistar rat hearts (n= 8-10) were isolated and allowed to equilibrat...

background: cardiovascular mortality and morbidity are high in chronic renal failure (crf) patients. increased dispersion of qt intervals is known to predispose to ventricular arrhythmias and sudden cardiac death. this study was conducted to assess the effect of hemodialysis (hd) on corrected qt (qtc) intervals and their dispersions (qtd) in chronic hemodialyzed patients. methods: fifty-eight p...

we are presenting a case illustrating atrial fibrillation (af) following the use of methylprednisolone in a patient with pelvic and femur fracture. a 48- year- old man with no significant past medical history, was admitted to the emergency department after injury in a car accident. he suffered a multiple bone fracture with chief complaints of pain and shortness of breath. he was transferred to ...

BACKGROUND Transcatheter occlusion has been applied to treat ostium secundum atrial septal defect (OS ASD) since 1997. During the clinical practice, several postoperative complications including arrhythmia have been reported. This study aimed to evaluate the value of the ratio of atrial septal occluder (ASO) versus atrial septal length (ASL) for predicting arrhythmia occurrence after transcathe...

IntroductIon Tachycardiomyopathies (TCMP) are an important cause of left ventricular (LV) dysfunction that should be recognised by physicians as they are potentially reversible and have a significant impact on morbidity and prognosis. They are classically defined as the reversible impairment of ventricular function induced by persistent arrhythmia. However, it is becoming increasingly evident t...

Arrhythmia is a common disease around the world and Helicobacter pylori (H. pylori) is a bacterium infecting 28% to 84% of subjects, depending on the population tested. However, the implication of H. pylori in cardiac arrhythmia is poorly understood. We performed this meta-analysis with an aim to identify the association between arrhythmia and H. pylori. We searched PubMed, Embase, Web of Scien...

Rac1 is a small GTPase and plays key roles in multiple cellular processes including the production of reactive oxygen species (ROS). However, whether Rac1 activation during myocardial ischaemia and reperfusion (I/R) contributes to arrhythmogenesis is not fully understood. We aimed to study the effects of Rac1 inhibition on store overload-induced Ca(2+) release (SOICR) and ventricular arrhythmia...