Modern medicine is currently marked by an increased interest in herbal pharmaceutical drugs traditionally applied folk a significant number of diseases. In this regard, saffron (Crocus sativus L. Iridaceae) particular importance. This paper presents the results study effects Azerbaijan-grown on blood level follicle-stimulating hormone (FSH) female rats, as well testosterone male rats. se...

Saffron or Crocus sativus L. (C. sativus) has been widely used as a medicinal plant to promote human health, especially in Asia. The main components of saffron are crocin, picrocrocin and safranal. The median lethal doses (LD50) of C. sativus are 200 mg/ml and 20.7 g/kg in vitro and in animal studies, respectively. Saffron has been suggested to be effective in the treatment of a wide range of d...

Objective: Exercise and nutrition as life style modification strategies for the prevention and control of diabetes are considered. The aim of present study was to assess the effects of saffron consumption and aerobic exercises on serum levels of Heart-type fatty acid binding protein (HFABP) and Troponin T in type2 diabetes (T2DM) patients. Materials and Methods: This study was a quasi-experime...

objective: a number of studies have demonstrated the potential antitumor effects of saffron and its constituents on different malignant cells in vitro. it has been reported that a novel glycoconjugate isolated from corms and callus of saffron possesses cytotoxic activity against different tumor cellswith nitric oxide (no) production. these data suggest that the cytotoxic effect of saffron extra...

Background: Obesity is pandemic worldwide and a strong risk factor for cardio-metabolic disorders. The few approved anti-obesity drugs have poor efficacy and safety profile. Thus, there is an urgent need for new anti-obesity agents. According to the traditional medicine and a clinical trial, saffron may have anorexigenic and anti-obesity effects which need further investigation. Objectives: Ev...

objective: the aim of the present study was to elucidate the possible biochemical improving effect in lipid metabolic that may result from continuous treatment with green tea extract in normal albino rats and those rendered hyperlipidemic by long term supplementation of fat-enriched diet. materials and methods: fifty male albino rats aged six weeks with 200±10 g weight were randomly divided int...

background: the cultivation of saffron is expanding through the southeast of iran, and allergy to saffron pollen occurs in workers involved in processing this plant. we aimed to clone, sequence and express a major allergen involved in saffron pollen allergy, and to compare the recombinant with the natural allergen. methods: the n-terminal amino acid sequence of cro s 1, an allergen from saffron...

Introduction: It has been reported that acute administration of morphine impairs learning and memory processes in rats. Furthermore, recent studies showed that Saffron extract improved ethanol-induced impairments of learning behaviors in mice, and also prevented ethanol-induced inhibition of hippocampal long-term potentiation. It can be postulated that there are some common mechanisms respon...