AIM To investigate the protective effect and its mechanism of lycium barbarum polysaccharides (LBP) against oxidative stress-induced apoptosis in human retinal pigment epithelial cells. METHODS ARPE-19 cells, a human retinal pigment epithelial cell lines, were exposed to different concentrations of H2O2 for 24h, then cell viability was measured by Cell Counting Kit-8 (CCK-8) assay to get the ...

Duringblastocyst formation, inner cellmass (ICM) cells differentiate into either epiblast (Epi) or primitive endoderm (PrE) cells, labeled by Nanog and Gata6, respectively, and organized in a salt-and-pepper pattern. Previous work in the mouse has shown that, in absence of Nanog, all ICMcells adopt aPrE identity.Moreover, the activationor the blockade of the Fgf/RTK pathway biases cell fate spe...

We revisit the enhanced target collision resistance (eTCR) property as a newly emerged notion of security for dedicated-key hash functions, which has been put forth by Halevi and Krawczyk at CRYPTO’06, in conjunction with the Randomized Hashing mode to achieve this property. Our contribution is twofold. Firstly, we provide a full picture of the relationships between eTCR and each of the seven s...

Avaliações nacionais e internacionais demonstram que estudantes brasileiros do ensino fundamental têm apre- sentado dificuldades no aprendizado comportamento de resolver problemas aritméticos. O objetivo deste estudo foi investigar, a partir um delineamento linha base múltipla (LBM) entre participantes, o efeito da formação classes equivalência diferentes formas apresentação envolvendo posições...

lentinan a polysaccharide from medicinal mushroom i.e lentinus, has been known to have anticancer properties. telomerase activity is not observed in normal healthy cells, whereas in cancerous cells telomerase expression is high. telomerase represents a promising cancer therapeutic target. we investigated the inhibitory effect of lentinan on telomerase reverse transcriptase gene (htert) which is...

lentiviral vectors are promising gene delivery tools capable of transducing a variety of dividing and non-dividing cells, including pluripotent stem cells which are refractory for transduction by murine retroviruses. although there is a growing debate on the safety of lentiviral vectors for gene transfer, in particular for those derived from human immunodeficiency viruses, type one (hiv-1) and ...

abstract background: schizophrenia is a severe mental disorder and numerous genes and loci are beleived to be involved in this disease. recent studies have reported a strong genetic association between dtnbp1 (dystrobrevin-binding protein 1) gene variants and schizophrenia. methods: in this research, we used a case-control study to establish the possible association between the p1635 (rs3213207...

the engineering of transgenic canola (brassica napus l. ) to make tolerance to the broad-spectrum herbicide, glyphosate, is one of the most effective approaches for weed management. glyphosate inhibits the enzyme epsps (5-enolpyruvylshikimate-3-phosphate synthase) enzyme which functions in the shikimate pathway and has a key role in biosynthesis of aromatic amino acids required for survival of ...