Neurology India | October-December 2008 | Vol 56 | Issue 4 with Cushing’s disease is approximately 80% whereas in children and adolescents it is approximately 47%.[1] The causes of hypertension in patients with Cushing’s disease are multifactorial. These include intrinsic glucocorticoid activity, activation of the renin-angiotensin system, and suppression of the vasodilatory systems.[1] Hyperte...

1. Latika SG, Ball S, Connolly V, James R, Kane P, Kelly W, et al. Pituitary apoplexy: A review of clinical presentation, management and outcome in 45 cases. Pituitary. 2004;7:157–63. 2. Nawar RN, AbdelMannan D, Selman WR, Arafah BM. Pituitary tumor apoplexy: a review. J Intensive Care Med. 2008;23: 75–90. 3. Ayuk J, McGregor EJ, Mitchell RD, Gittoes NJL. Acute management of pituitary apoplexys...

Hypopituitarism is defined as deficiency of all anterior pituitary hormone1. Panhypopituitarism when there both and posterior hormone. In this case report our 50 year old male diagnosed with apoplexy (bleeding in rathke’s pouch) started on intravenous steroids later oral he improving clinically.

Pituitary apoplexy is characterized by sudden increase in pituitary gland volume secondary to ischemia and/or necrosis, usually in a pituitary adenoma. Most cases occur during the 5th decade of life, predominantly in males and in previously unknown clinically non-functioning pituitary adenomas. There are some predisposing factors as arterial hypertension, anticoagulant therapy and major surgery...

A 41-yr-old man was admitted with acute headache, neck stiffness, and febrile sensation. Cerebrospinal fluid examination showed pleocytosis, an increased protein level and, a decreased glucose concentration. No organisms were observed on a culture study. An imaging study revealed pituitary macroadenoma with hemorrhage. On the 7th day of the attack, confusion, dysarthria, and right-sided facial ...

headache, vision loss, and ophthalmoplegia from pituitary hemorrhage or infarction characterize pituitary apoplexy,1,3,6–8 and MR imaging of the brain often demonstrates a pituitary mass with heterogeneous signal due to the presence of blood.7 Apoplexy typically occurs in a previously unrecognized pituitary adenoma, but it can also occur when the pituitary gland is normal. Various precipitating...